Evidence map›Paper›PMID 33156569›Full record

ArticleHuman brain mapping2021

A comprehensive study on electroencephalography and magnetoencephalography sensitivity to cortical and subcortical sources.

Maria Carla Piastra, Andreas Nüßing, Johannes Vorwerk, Maureen Clerc, Christian Engwer, Carsten H Wolters

Abstract read
In one paragraph

Article in Human brain mapping, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed.

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  17. MEG in MRI-Negative Patients with Focal Epilepsy.Journal of clinical medicine · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maria Carla PiastraInstitute for Biomagnetism and Biosignalanalysis, University of Münster, Münster, Germany.ORCID 0000-0001-8339-0355
Andreas NüßingInstitute for Biomagnetism and Biosignalanalysis, University of Münster, Münster, Germany.
Johannes VorwerkInstitute of Electrical and Biomedical Engineering, University for Health Sciences, Medical Informatics and Technology, Hall in Tirol, Austria.ORCID 0000-0003-3597-4203
Maureen ClercInria Sophia Antipolis-Mediterranée, Biot, France.
Christian EngwerInstitute for Computational and Applied Mathematics, University of Münster, Münster, Germany.
Carsten H WoltersInstitute for Biomagnetism and Biosignalanalysis, University of Münster, Münster, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Signal-to-noise ratio (SNR) maps are a good way to visualize electroencephalography (EEG) and magnetoencephalography (MEG) sensitivity. SNR maps extend the knowledge about the modulation of EEG and MEG signals by source locations and orientations and can therefore help to better understand and interpret measured signals as well as source reconstruction results thereof. Our work has two main objectives. First, we investigated the accuracy and reliability of EEG and MEG finite element method (FEM)-based sensitivity maps for three different head models, namely an isotropic three and four-compartment and an anisotropic six-compartment head model. As a result, we found that ignoring the cerebrospinal fluid leads to an overestimation of EEG SNR values. Second, we examined and compared EEG and MEG SNR mappings for both cortical and subcortical sources and their modulation by source location and orientation. Our results for cortical sources show that EEG sensitivity is higher for radial and deep sources and MEG for tangential ones, which are the majority of sources. As to the subcortical sources, we found that deep sources with sufficient tangential source orientation are recordable by the MEG. Our work, which represents the first comprehensive study where cortical and subcortical sources are considered in highly detailed FEM-based EEG and MEG SNR mappings, sheds a new light on the sensitivity of EEG and MEG and might influence the decision of brain researchers or clinicians in their choice of the best modality for their experiment or diagnostics, respectively.

Indexed as

AdultAmygdalaCerebellumCerebral CortexCorpus StriatumElectroencephalographyEvoked Potentials, SomatosensoryHippocampusHumansMagnetic Resonance ImagingMagnetoencephalographyReproducibility of ResultsSignal-To-Noise RatioThalamuselectroencephalographyfinite element methodmagnetoencephalographysensitivity mapsignal-to-noise ratiosubcortical sourcesvolume conduction modeling

Identifiers

PMID33156569
PMCPMC7856654

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.