Evidence map›Paper›PMID 33156520›Full record

ArticleJournal of the American Geriatrics Society2021

Evolution of Basic Activities of Daily Living Function in Older Patients One Year After Transcatheter Aortic Valve Implantation.

Dominic Bertschi, André Moser, Stefan Stortecky, Marcel Zwahlen, Stephan Windecker, Thierry Carrel, Andreas E Stuck, Andreas W Schoenenberger

Open access · hybridAbstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Dominic BertschiDepartment of Geriatrics, Bern University Hospital, University of Bern, Bern, Switzerland.
André MoserEpidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.
Stefan StorteckyDepartment of Cardiology, Swiss Cardiovascular Center Bern, Bern University Hospital, University of Bern, Bern, Switzerland.
Marcel ZwahlenInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.ORCID 0000-0002-6772-6346
Stephan WindeckerDepartment of Cardiology, Swiss Cardiovascular Center Bern, Bern University Hospital, University of Bern, Bern, Switzerland.
Thierry CarrelDepartment of Cardiovascular Surgery, Bern University Hospital, University of Bern, Bern, Switzerland.
Andreas E StuckDepartment of Geriatrics, Bern University Hospital, University of Bern, Bern, Switzerland.
Andreas W SchoenenbergerDepartment of Geriatrics, Bern University Hospital, University of Bern, Bern, Switzerland.
University of Bern · CHUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesTo assess the course and prediction of basic activities of daily living (ADL) function in patients after transcatheter aortic valve implantation (TAVI).

designThis was a prospective cohort study.

settingThe setting was a single academic center in Switzerland.

participantsParticipants included individuals aged ≥70 years (n = 330) undergoing TAVI. MEASUREMENTS: A frailty index (based on geriatric assessment) and cardiac risk scores (EuroSCORE, Society of Thoracic Surgeons [STS] score) were determined in patients before TAVI. Basic ADL function was measured with patient or proxy interviews at baseline and 1-year follow up. We used logistic regression models to investigate the association between baseline factors and functional decline.

resultsAt 1-year follow up, 229 (69.4%) of the 330 patients had stable or improved basic ADL function, 49 (14.8%) experienced a decline in basic ADL function, and 52 (15.8%) died. The frailty index, but not cardiac risk scores, significantly predicted decline in basic ADL function. Among the 34 surviving very frail patients, 12 (35.3%) experienced a functional status decline, and the remaining 22 (64.7%) had stable or improved functional status at 1-year follow up.

conclusionThis study confirms that a frailty index, and not cardiac risk scores, identifies patients at an increased risk of functional status decline after TAVI. Identifying patients with a high frailty index before TAVI is clinically relevant as these patients might benefit from targeted geriatric management and rehabilitation after TAVI. However, based on current data, it is not justified to use information on frailty status as the criterion for identifying patients in whom TAVI might be futile. Although the probability of poor outcome is high, very frail patients also have a high probability of favorable long-term functional outcome.

Indexed as

Activities of Daily LivingAortic Valve StenosisFrailtyFunctional StatusGeriatric AssessmentAgedCohort StudiesFemaleFrail ElderlyHeart Disease Risk FactorsHumansMalePreoperative PeriodPrognosisRisk AssessmentSwitzerlandaortic stenosiscardiac risk scorescognitive assessmentfunctional statusfutilitygeriatric assessmentrisk stratification

Identifiers

PMID33156520
PMCPMC7894317
OpenAlexW3095721381

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.