Evidence map›Paper›PMID 33156508›Full record

ArticleNetherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation2021

Waiting list mortality and the potential of donation after circulatory death heart transplantations in the Netherlands.

S Roest, S E Kaffka Genaamd Dengler, V van Suylen, N P van der Kaaij, K Damman, L W van Laake, J A Bekkers, M Dalinghaus, M E Erasmus, O C Manintveld

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In one paragraph

Article in Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Observational
  4. Article
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  7. Healthcare consumption of patients with left ventricular assist device: real-world data.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2024
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  8. Article
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  11. Review
  12. Left ventricular assist device implantation and clinical outcomes in the Netherlands.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2023
    Article
  13. Review
  14. Organ Donation After Euthanasia in Patients Suffering From Psychiatric Disorders: 10-Years of Preliminary Experiences in the Netherlands.Transplant international : official journal of the European Society for Organ Transplantation · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

S RoestDepartment of Cardiology, Thorax Centre, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands.
S E Kaffka Genaamd DenglerDepartment of Cardiothoracic Surgery, University Medical Centre Utrecht, Utrecht, The Netherlands.
V van SuylenDepartment of Cardiothoracic Surgery, University Medical Centre Groningen, Groningen, The Netherlands.
N P van der KaaijDepartment of Cardiothoracic Surgery, University Medical Centre Utrecht, Utrecht, The Netherlands.
K DammanDepartment of Cardiology, University Medical Centre Groningen, Groningen, The Netherlands.
L W van LaakeDepartment of Cardiology, University Medical Centre Utrecht, Utrecht, The Netherlands.
J A BekkersDepartment of Cardiothoracic Surgery, Thorax Centre, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands.
M DalinghausDepartment of Paediatrics, Division of Paediatric Cardiology, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands.
M E ErasmusDepartment of Cardiothoracic Surgery, University Medical Centre Groningen, Groningen, The Netherlands.
O C ManintveldDepartment of Cardiology, Thorax Centre, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands. o.manintveld@erasmusmc.nl.
Erasmus MC · NLUniversity Medical Center Groningen · NLUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWith more patients qualifying for heart transplantation (HT) and fewer hearts being transplanted, it is vital to look for other options. To date, only organs from brain-dead donors have been used for HT in the Netherlands. We investigated waiting list mortality in all Dutch HT centres and the potential of donation after circulatory death (DCD) HT in the Netherlands.

methodsTwo different cohorts were evaluated. One cohort was defined as patients who were newly listed or were already on the waiting list for HT between January 2013 and December 2017. Follow-up continued until September 2018 and waiting list mortality was calculated. A second cohort of all DCD donors in the Netherlands (lung, liver, kidney and pancreas) between January 2013 and December 2017 was used to calculate the potential of DCD HT.

resultsOut of 395 patients on the waiting list for HT, 196 (50%) received transplants after a median waiting time of 2.6 years. In total, 15% died while on the waiting list before a suitable donor heart became available. We identified 1006 DCD donors. After applying exclusion criteria and an age limit of 50 years, 122 potential heart donors remained. This number increased to 220 when the age limit was extended to 57 years.

conclusionWaiting list mortality in the Netherlands is high. HT using organs from DCD donors has great potential in the Netherlands and could lead to a reduction in waiting list mortality. Cardiac screening will eventually determine the true potential.

Indexed as

Donation after circulatory deathHeart transplantationMortalityWaiting list

Identifiers

PMID33156508
PMCPMC7843666
OpenAlexW3095111152

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.