ReviewCell and tissue research2020
The identification of neuronal control pathways supplying effector tissues in the stomach.
Review in Cell and tissue research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 33 citations in OpenAlex.
- Anatomy and function of efferent and afferent vagal innervation of the stomach.Autonomic neuroscience : basic & clinical · 2026Review
- Types of Neurons in the Myenteric Plexus of Human Gastric Corpus Identified by Multi-Layer Immunohistochemical Coding and Vagal Tracing.Neurogastroenterology and motility · 2026Article
- Gastroparesis Phenotyping: Current Methods and Emerging Opportunities With Magnetic Resonance Imaging.Neurogastroenterology and motility · 2026Review
- Changes in interstitial cells of Cajal calcium activity in a diabetic mouse model of delayed gastric emptying.The Journal of physiology · 2026Article
- Article
- Rewiring the Brain Through the Gut: Insights into Microbiota-Nervous System Interactions.Current issues in molecular biology · 2025Review
- Pharmacologic treatments for gastroparesis.Pharmacological reviews · 2025Review
- Surface mapping of gastric motor functions using MRI: a comparative study between humans and rats.American journal of physiology. Gastrointestinal and liver physiology · 2024Article
- Neural regulation of slow waves and phasic contractions in the distal stomach: a mathematical model.Journal of neural engineering · 2024Article
- Organization and morphology of calcitonin gene-related peptide-immunoreactive axons in the whole mouse stomach.The Journal of comparative neurology · 2023Article
- Topographical distribution and morphology of SP-IR axons in the antrum, pylorus, and duodenum of mice.Autonomic neuroscience : basic & clinical · 2023Article
- The enteric nervous system.Physiological reviews · 2023Review
- Topographical organization and morphology of substance P (SP)-immunoreactive axons in the whole stomach of mice.The Journal of comparative neurology · 2023Article
- Computational models of autonomic regulation in gastric motility: Progress, challenges, and future directions.Frontiers in neuroscience · 2023Review
- The vagus nerve mediates the stomach-brain coherence in rats.NeuroImage · 2022Article
- High-resolution ultrasound and speckle tracking: a non-invasive approach to assess in vivo gastrointestinal motility during development.Development (Cambridge, England) · 2022Article
- Organisation of the musculature of the rat stomach.Journal of anatomy · 2022Article
- Morphologies, dimensions and targets of gastric nitric oxide synthase neurons.Cell and tissue research · 2022Article
- Functional human gastrointestinal organoids can be engineered from three primary germ layers derived separately from pluripotent stem cells.Cell stem cell · 2022Article
- Gastroparesis.Gastroenterology · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
Abstract
The stomach acts as a buffer between the ingestion of food and its processing in the small intestine. It signals to the brain to modulate food intake and it in turn regulates the passage of a nutrient-rich fluid, containing partly digested food, into the duodenum. These processes need to be finely controlled, for example to restrict reflux into the esophagus and to transfer digesta to the duodenum at an appropriate rate. Thus, the efferent pathways that control gastric volume, gastric peristalsis and digestive juice production are critically important. We review these pathways with an emphasis on the identities of the final motor neurons and comparisons between species. The major types of motor neurons arising from gastric enteric ganglia are as follows: immunohistochemically distinguishable excitatory and inhibitory muscle motor neurons; four neuron types innervating mucosal effectors (parietal cells, chief cells, gastrin cells and somatostatin cells); and vasodilator neurons. Sympathetic efferent neurons innervate intramural arteries, myenteric ganglia and gastric muscle. Vagal efferent neurons with cell bodies in the brain stem do not directly innervate gastric effector tissues; they are pre-enteric neurons that innervate each type of gastric enteric motor neuron. The principal transmitters and co-transmitters of gastric motor neurons, as well as key immunohistochemical markers, are the same in rat, pig, human and other species.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.