Evidence map›Paper›PMID 33155970›Full record

ArticlePreventing chronic disease2020

Urban-Rural Disparities in Access to Low-Dose Computed Tomography Lung Cancer Screening in Missouri and Illinois.

Karthik W Rohatgi, Christine M Marx, Marquita W Lewis-Thames, Jingxia Liu, Graham A Colditz, Aimee S James

Erratum issuedAbstract read
In one paragraph

Article in Preventing chronic disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Knowledge translation strategies to enhance lung cancer screening programme implementation: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2025
    Pooled it
  2. Predictors of Cessation Readiness among Cigarette Smokers Presenting for Low-Dose CT Lung Cancer Screening in Community Settings (WF-20817CD).Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
    Trial
  3. Clinical Decision Support with or without Shared Decision Making to Improve Preventive Cancer Care: A Cluster-Randomized Trial.Medical decision making : an international journal of the Society for Medical Decision Making · 2022
    Trial
  4. Geographic Access to Low-Dose CT Lung Cancer Screening in Tennessee: Disparities by Socioeconomic Variables, Rurality, and Appalachian Status.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2026
    Article
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  9. Disparities of Distant Metastasis Evaluation Imaging for Rectal Cancer.Journal of the American College of Radiology : JACR · 2025
    Article
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  13. Review
  14. Using Telehealth to Increase Lung Cancer Screening Referrals for At-Risk Veterans in Rural Communities.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2024
    Article
  15. Review
  16. Review
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  18. Alvin J. Siteman Cancer Center: Cancer Prevention Perspective.Cancer prevention research (Philadelphia, Pa.) · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Karthik W RohatgiDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri.
Christine M MarxDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri.
Marquita W Lewis-ThamesDepartment of Medical Social Sciences, Center for Community Health, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Jingxia LiuDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri.
Graham A ColditzDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri.
Aimee S JamesDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri.

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI AIMEE S JAMES · 2001 to 2026
$128.0M
Postdoctoral Training in Cancer Prevention and ControlT32CA190194 · NCI · WASHINGTON UNIVERSITY · PI GRAHAM A. COLDITZ, AIMEE S JAMES · 2014 to 2026
$4.7M
NCI NIH HHS P30 CA091842NCI NIH HHS T32 CA190194
6 · The paper itself

Abstract

introductionLow-dose computed tomography (LDCT) lung cancer screening is recommended for current and former smokers who meet eligibility criteria. Few studies have quantitatively examined disparities in access to LDCT screening. The objective of this study was to examine relationships between 1) rurality, sociodemographic characteristics, and access to LDCT lung cancer screening and 2) screening access and lung cancer mortality.

methodsWe used census block group and county-level data from Missouri and Illinois. We defined access to screening as presence of an accredited screening center within 30 miles of residence as of May 2019. We used mixed-effects logistic models for screening access and county-level multiple linear regression models for lung cancer mortality.

resultsApproximately 97.6% of metropolitan residents had access to screening, compared with 41.0% of nonmetropolitan residents. After controlling for sociodemographic characteristics, the odds of having access to screening in rural areas were 17% of the odds in metropolitan areas (95% CI, 12%-26%). We observed no association between screening access and lung cancer mortality. Southeastern Missouri, a rural and impoverished area, had low levels of screening access, high smoking prevalence, and high lung cancer mortality.

conclusionAlthough access to LDCT is lower in rural areas than in urban areas, lung cancer mortality in rural residents is multifactorial and cannot be explained by access alone. Targeted efforts to implement rural LDCT screening could reduce geographic disparities in access, although further research is needed to understand how increased access to screening could affect uptake and rural disparities in lung cancer mortality.

Indexed as

AgedEarly Detection of CancerFemaleHealthcare DisparitiesHumansIllinoisLung NeoplasmsMaleMass ScreeningMiddle AgedMissouriPrevalenceRural PopulationSmokingTomography, X-Ray ComputedUrban Population

Identifiers

PMID33155970
PMCPMC7665516

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.