Evidence map›Paper›PMID 33155824›Full record

Trial reportDiabetes technology & therapeutics2021

Clinical Management and Pump Parameter Adjustment of the Control-IQ Closed-Loop Control System: Results from a 6-Month, Multicenter, Randomized Clinical Trial.

Grenye O'Malley, Laurel H Messer, Carol J Levy, Jordan E Pinsker, Gregory P Forlenza, Elvira Isganaitis, Yogish C Kudva, Laya Ekhlaspour, Dan Raghinaru, John Lum and 2 more

Registry-linked trialOpen access · greenAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Diabetes technology & therapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04838561 (Assessing the Impact of Control-IQ Technology on Quality of Life and Glycemic Control in Children and Youth With Type 1 Diabetes in a Canadian Context), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04838561 completednot on this map

Assessing the Impact of Control-IQ Technology on Quality of Life and Glycemic Control in Children and Youth With Type 1 Diabetes in a Canadian Context

TypeobservationalSponsorChildren's Hospital of Eastern OntarioRan2021 to 2021Enrolled65ConditionsType 1 Diabetes
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. The Hybrid Closed-Loop System Tandem t:slim X2™ with Control-IQ Technology: Expert Recommendations for Better Management and Optimization.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2024
    Article
  6. A Systematic Review of Commercial Hybrid Closed-Loop Automated Insulin Delivery Systems.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2023 · on this map
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 1 country.

Grenye O'MalleyDivision of Endocrinology, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.
Laurel H MesserBarbara Davis Center for Diabetes, University of Colorado, Aurora, Colorado, USA.
Carol J LevyDivision of Endocrinology, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.
Jordan E PinskerSansum Diabetes Research Institute, Santa Barbara, California, USA.
Gregory P ForlenzaBarbara Davis Center for Diabetes, University of Colorado, Aurora, Colorado, USA.
Elvira IsganaitisResearch Division, Joslin Diabetes Center and Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.
Yogish C KudvaDivision of Endocrinology, Diabetes, Metabolism and Nutrition, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Laya EkhlaspourDivision of Pediatric Endocrinology and Diabetes, Department of Pediatrics, Stanford University School of Medicine, Stanford, California, USA.
Dan RaghinaruJaeb Center for Health Research, Tampa, Florida, USA.
John LumJaeb Center for Health Research, Tampa, Florida, USA.
Sue A BrownDivision of Endocrinology, Department of Medicine, Center for Diabetes Technology, University of Virginia, Charlottesville, Virginia, USA.
iDCL Trial Research Group
University of Colorado Anschutz Medical Campus · USIcahn School of Medicine at Mount Sinai · USJaeb Center for Health Research · USJoslin Diabetes Center · USMayo Clinic · USSansum Diabetes Research Institute · USStanford Medicine · USUniversity of Colorado Colorado Springs · USUniversity of Virginia · US

Funding

SPECIAL ASSAY COREP30DK036836 · NIDDK · JOSLIN DIABETES CENTER · PI Alessandro Doria · 1986 to 2026
$50.5M
Data Coordinating Center for Artificial Pancreas StudiesU24DK123768 · NIDDK · JAEB CENTER FOR HEALTH RESEARCH, INC. · PI BECK, ROY W. · 2019 to 2020
$1.3M
Modeling and modulating insulin delivery in automated insulin delivery systems to accommodate for meal compositionsK23DK121942 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI EKHLASPOUR, LAYA · 2020 to 2024
$964k
NIDDK NIH HHS K23 DK121942NIDDK NIH HHS P30 DK036836NIDDK NIH HHS U24 DK123768
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Diabetes Mellitus, Type 1Insulin Infusion SystemsBlood Glucose Self-MonitoringHumansHypoglycemic AgentsInsulinHypoglycemic AgentsInsulinAutomated insulin deliveryClosed-loop controlContinuous glucose monitorPump parametersType 1 diabetes

Identifiers

PMID33155824
PMCPMC8114941
OpenAlexW3097482725

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.