ArticleActa orthopaedica et traumatologica turcica2020
Intravenous tranexamic acid for reducing perioperative blood loss during revision hip arthroplasty: A retrospective study.
Article in Acta orthopaedica et traumatologica turcica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 5 citations in OpenAlex.
- The Efficacy and Safety of Tranexamic Acid in Revision Total Knee and Total Hip Arthroplasty: A Systematic Review and Meta-Analysis.Arthroplasty today · 2026Article
- Early clinical outcomes of bipolar hemiarthroplasty for femoral neck fractures in elderly patients using the OCM approach: a retrospective study.Frontiers in surgery · 2024Article
- The Watson Extraction System for removal of well-fixed femoral stems: A retrospective review of 10 cases.Journal of orthopaedics · 2023Article
- Influencing factors of hidden blood loss after primary total hip arthroplasty through the posterior approach: a retrospective study.BMC musculoskeletal disorders · 2023Article
- The efficacy and safety of intravenous tranexamic acid on blood loss during total ankle replacement: a retrospective study.Scientific reports · 2022Article
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Authors and funding
5 authors at 2 institutions in 1 country.
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Abstract
objectiveThis study aimed to explore the efficacy and safety of intravenous tranexamic acid (TXA) for reducing perioperative blood loss and allogeneic blood transfusions in revision hip arthroplasty.
methodsTXA was routinely administered as an intravenous preoperative dose in all the revision hip arthroplasty cases in our institution from December 2012. We retrospectively reviewed 803 patients who underwent revision hip arthroplasty from January 2008 to September 2018. These patients were divided into 2 groups based on whether they received intravenous TXA (n=482; 231 men and 251 women; mean age: 63.27±11.73 years) or not (n=321; 159 men and 162 women; mean age: 63.91±11.69 years). The 2 groups were compared in terms of estimated intraoperative blood loss, visible blood loss, hidden blood loss, the rate and volume of allogeneic blood transfusions, and the incidence of symptomatic venous thromboembolism. The patients were also compared depending on whether they underwent total hip revision, isolated acetabular revision, or isolated femoral revision.
resultsRegardless of the type of revision involved, the patients who received TXA showed significantly lower estimated intraoperative blood loss, visible blood loss, hidden blood loss, and allogeneic blood transfusion rate and volume (all p values were less than 0.001). Use of TXA was not associated with significant changes in the incidence of postoperative symptomatic venous thromboembolism (p=0.911). Similar results were obtained with subgroups of patients who underwent different types of revision surgeries, except hidden blood loss (p=0.994) of patients in the isolated femoral revision subgroup.
conclusionThe administration of intravenous TXA can safely and effectively reduce the perioperative blood loss and allogeneic blood transfusions in revision hip arthroplasty. LEVEL OF EVIDENCE: Level III, Therapeutic study.
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