Evidence map›Paper›PMID 33155515›Full record

ArticleSLAS discovery : advancing life sciences R & D2021

Saporin, a Polynucleotide-Adenosine Nucleosidase, May Be an Efficacious Therapeutic Agent for SARS-CoV-2 Infection.

Idris Arslan, Hafize Akgul, Murat Kara

Open access · hybridAbstract read
In one paragraph

Article in SLAS discovery : advancing life sciences R & D, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Unlocking saponin biosynthesis in soapwort.Nature chemical biology · 2025
    Article
  4. A20 as a Potential Therapeutic Target for COVID-19.Immunity, inflammation and disease · 2025
    Review
  5. Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Idris ArslanBiomedical Engineeing, Bulent Ecevit University, Incivez, Zonguldak, Turkey.ORCID 0000-0001-7634-7148
Hafize AkgulGraduate School of Natural and Applied Sciences, Nanotechnology Engineeing, Bulent Ecevit University, Incivez, Zonguldak, Turkey.
Murat KaraGraduate School of Natural and Applied Sciences, Nanotechnology Engineeing, Bulent Ecevit University, Incivez, Zonguldak, Turkey.
Bülent Ecevit University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Saporin, a type I ribosome-inactivating protein from soapwort plant, is a potent protein synthesis inhibitor. Catalytically, saporin is a characteristic

Indexed as

COVID-19 Drug TreatmentAntiviral AgentsApoptosisHumansImmunotoxinsNADPoly(ADP-ribose) PolymerasesSaporinsSignal TransductionAntiviral AgentsImmunotoxinsNADPoly(ADP-ribose) PolymerasesSaporinsabasic siteN-glycosidaserRNAsaporinSARS-CoV-2

Identifiers

PMID33155515
PMCPMC8940857
OpenAlexW3096704832

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.