Evidence map›Paper›PMID 33155160›Full record

ArticleClinical rheumatology2021

Management of psoriatic arthritis in rheumatology and dermatology settings: sub-analysis of the Italian population from the international LOOP study.

Ennio Lubrano, Andrea Delle Sedie, Marco Romanelli, Maria Sole Chimenti, Luca Bianchi, Stefano Piaserico, Catia De Felice, Dario Graceffa, Maria Ilenia De Andres, Salvatore Curatolo and 28 more

Abstract read
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In one paragraph

Article in Clinical rheumatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

38 authors at 18 institutions in 1 country.

Ennio LubranoDipartimento di Medicina e Scienze della Salute "Vincenzo Tiberio", Università degli Studi del Molise, Via Giovanni Paolo II, C/da Tappino, 86100, Campobasso, Italy. enniolubrano@hotmail.com.
Andrea Delle SedieRheumatology Unit, University of Pisa, Pisa, Italy.
Marco RomanelliDepartment of Dermatology, University of Pisa, Pisa, Italy.
Maria Sole ChimentiRheumatology, Allergology and Clinical Immunology, Department of "Medicina dei Sistemi", University of Rome Tor Vergata, Rome, Italy.
Luca BianchiDermatology, Department of Systems Medicine, Tor Vergata University of Rome, Rome, Italy.
Stefano PiasericoDermatology Unit, Department of Medicine, University of Padova, Padova, Italy.
Catia De FeliceDepartment of Clinical Dermatology, San Gallicano Dermatological Institute IRCCS, Rome, Italy.
Dario GraceffaDepartment of Clinical Dermatology, San Gallicano Dermatological Institute IRCCS, Rome, Italy.
Maria Ilenia De AndresARNAS Garibaldi UO Department of Rheumatology, Catania, Italy.
Salvatore CuratoloARNAS Garibaldi UO Department of Dermatology, Catania, Italy.
Rosa Daniela GrembialeRheumatology Research Unit, Department of Health Sciences, "Magna Graecia" University, Catanzaro, Italy.
Stefano DastoliDermatology Unit, Department of Health Sciences, "Magna Graecia" University, Catanzaro, Italy.
Chiara ArcuriARNAS Civico Di Palermo, UOC Reumatologia, Palermo, Italy.
Rosa Giuseppa AngileriARNAS Civico Di Palermo, UOC Dermatologia, Palermo, Italy.
Francesca PrignanoDermatology Clinic - ASF, Department of Health Sciences, University of Florence, Florence, Italy.
Francesca BandinelliRheumatology Unit, San Giovanni di Dio Hospital, Florence, Italy.
Elena BaldisseraUnit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital, Vita-Salute, Milan, Italy.
Santo Raffaele MercuriUnit of Dermatology and Cosmetology, IRCCS University San Raffaele, Vita-Salute, Milan, Italy.
Chiara FranchiUO Dermatologia, IRCCS Galeazzi, Milan, Italy.
Matteo LonghiUO Reumatologia, IRCCS Galeazzi, Milan, Italy.
Angela PatrìDepartment of Dermatology, University of Naples Federico II, Naples, Italy.
Francesco CasoRheumatology Unit, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.
Giuseppe PassiuRheumatology Unit, Department of Clinical and Experimental Medicine, University of Sassari, Sassari, Italy.
Maria Antonia MontesuDepartment of Surgical, Microsurgical and Medical Sciences, Dermatology, University of Sassari, Sassari, Italy.
Simone ParisiRheumatology Unit, Azienda Ospedaliera Città della Salute e della Scienza di Torino, Turin, Italy.
Elena StroppianaDermatology Unit, A.O.U Città della Salute e della Scienza di Torino, Turin, Italy.
Genoveffa Scotto di LuzioAO Caserta San Sebastiano e Sant Anna UOS Di Dermatologia, Caserta, Italy.
Giovanni ItalianoAO Caserta San Sebastiano e Sant Anna UOS Medicina Interna, Caserta, Italy.
Sergio Di NuzzoDepartment of Medicine and Surgery (DiMeC), University of Parma, Parma, Italy.
Daniele SantilliDepartment of General and Specialist Medicine, Internal Medicine and Rheumatology Unit, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.
Laura BigiDermatology Unit, Azienda Ospedaliero-Universitaria Policlinico di Modena, Modena, Italy.
Federica LumettiRheumatology Unit, Azienda Ospedaliero-Universitaria di Modena, University of Modena and Reggio Emilia, Modena, Italy.
Concetto Paolo AgnusdeiAzienda Sanitaria Regionale Molise, OO.CC. Cardarelli, UO Dermatologia, Campobasso, Italy.
Maria Grazia FerrucciDepartment of Rheumatology, AO San Pio, Benevento, Italy.
Giuliana GualbertiAbbVie SrL, Rome, Italy.
Francesca MarandoAbbVie SrL, Rome, Italy.ORCID http://orcid.org/0000-0001-5989-3112
Roberta RamondaRheumatology Unit, Department of Medicine - DIMED, University of Padua, Padua, Italy.
Francesco CusanoUOC di Dermatologia, AO San Pio di Benevento, Benevento, Italy.
Azienda Ospedaliera Citta' della Salute e della Scienza di Torino · ITIstituto Ortopedico Galeazzi · ITMagna Graecia University · ITOspedale Garibaldi · ITSan Gallicano Hospital · ITUniversity of Naples Federico II · ITUniversity of Padua · ITUniversity of Pisa · ITUniversity of Rome Tor Vergata · ITUniversity of Sassari · ITVita-Salute San Raffaele University · ITAzienda Ospedaliero-Universitaria di Modena · ITNuovo Ospedale San Giovanni di Dio · ITOspedale di Parma · ITUniversity of Florence · ITUniversity of Modena and Reggio Emilia · ITUniversity of Molise · ITUniversity of Parma · IT

Funding

AbbVie SRL N/A
6 · The paper itself

Abstract

Psoriatic arthritis (PsA) patients are often treated by dermatology and rheumatology specialities and may receive different treatments. To evaluate the impact of dermatology/rheumatology specialist settings on diagnosis and therapeutic approach in PsA patients. This cross-sectional multicounty study in Italy involved twenty-eight rheumatology or dermatology clinics. Patients with suspected or confirmed PsA were examined by both a dermatologist and a rheumatologist. A total of 413 patients were enrolled and 347 (84%) were diagnosed with PsA. The majority of patients were enrolled from a rheumatology setting (N = 224, 64.6%). Patients with PsA in the dermatology settings had significantly higher disease activity, including skin involvement and musculoskeletal symptoms. Time from PsA onset to diagnosis was 22.3 ± 53.8 vs. 39.4 ± 77.5 months (p = 0.63) in rheumatology and dermatology settings; time from diagnosis to initiation of csDMARD was 7.3 ± 27.5 vs. 19.5 ± 50.6 months, respectively (p < 0.001). In contrast, time from diagnosis to bDMARD use was shorter in dermatology settings (54.9 ± 69 vs. 44.2 ± 65.6 months, p = 0.09, rheumatology vs. dermatology), similar to the time taken from first csDMARDs and bDMARDs (48.7 ± 67.9 vs. 35.3 ± 51.9 months, p = 0.34). The choice to visit a rheumatologist over a dermatologist was positively associated with female gender and swollen joints and negatively associated with delay in time from musculoskeletal symptom onset to PsA diagnosis. This study highlights a diagnostic delay emerging from both settings with significantly different therapeutic approaches. Our data reinforce the importance of implementing efficient strategies to improve early identification of PsA that can benefit from the integrated management of PsA patients. Key Points • A diagnostic delay was observed from both dermatology and rheumatology settings with significantly different therapeutic approaches. • Shared dermatology and rheumatology clinics offer the combined expertise to improve in the early identification and management of PsA.

Indexed as

Arthritis, PsoriaticDermatologyPsoriasisRheumatologyCross-Sectional StudiesDelayed DiagnosisFemaleHumansItalyBiological drugsDermatologyDiagnosisManagementPsoriatic arthritisRheumatology

Identifiers

PMID33155160
OpenAlexW3095316427

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.