Evidence map›Paper›PMID 33155049›Full record

ArticlePain medicine (Malden, Mass.)2021

An Interventional Pain Algorithm for the Treatment of Postmastectomy Pain Syndrome: A Single-Center Retrospective Review.

Ajax Yang, Danielle Nadav, Aron Legler, Grant H Chen, Lee Hingula, Vinay Puttanniah, Amitabh Gulati

Open access · greenAbstract read
In one paragraph

Article in Pain medicine (Malden, Mass.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Ultrasound-guided fascial plane blocks in chronic pain: a narrative review.Journal of anesthesia, analgesia and critical care · 2024
    Review
  3. Review
  4. Postmastectomy Functional Impairments.Current oncology reports · 2023
    Review
  5. Review
  6. Article
  7. Pain associated with breast cancer: etiologies and therapies.Frontiers in pain research (Lausanne, Switzerland) · 2023
    Review
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ajax YangDepartment of Anesthesiology and Critical Care, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Danielle NadavDepartment of Anesthesiology and Critical Care, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Aron LeglerDepartment of Anesthesiology and Critical Care, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Grant H ChenDepartment of Anesthesiology and Critical Care, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Lee HingulaDepartment of Anesthesiology and Critical Care, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Vinay PuttanniahDepartment of Anesthesiology and Critical Care, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Amitabh GulatiDepartment of Anesthesiology and Critical Care, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Memorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

objectiveBreast cancer is the most common female malignancy worldwide. Breast surgery and adjuvant oncological therapies are often required to increase survival. Treatment-related pain may persist and evolve into postmastectomy pain syndrome (PMPS) in a significant subset of breast cancer survivors. In this retrospective investigation, we will present our experience in applying an interventional algorithmic approach to treat PMPS.

designA retrospective study.

settingAn academic cancer hospital. SUBJECTS: Adult females with PMPS diagnosis.

methodsWe reviewed 169 records with the diagnosis of PMPS from 2015 to 2019 within our health system. Pre- and post-injection pain scores, relief duration, and medication usage changes were collected. The decision to perform each procedure was based on the anatomic location of the painful area with the corresponding peripheral sensory innervation. Decision-making flow diagrams were created to present our experience in managing PMPS beyond peripheral nerve blocks.

resultsUltrasound-guided peripheral nerve block results (n=350) were analyzed. The mean baseline pain score was 7, compared with the post-treatment mean score of 3 (95% confidence interval: 3.58 to 3.98, P = 0.0001). Among the responders, the mean pain relief duration was 45 days, with a median of 84 days. Opioid medication consumption was reduced by 11% (t = 0.72, P = 0.47).

conclusionsUltrasound-guided nerve blocks of this area could be performed safely and effectively after breast surgeries. We also present our proposed algorithm to provide a stepwise application for selecting the appropriate therapies in the management of more complex PMPS.

Indexed as

Breast NeoplasmsAdultAlgorithmsFemaleHumansMastectomyPostoperative PainRetrospective StudiesUltrasonography, InterventionalCancer PainNerve BlockPostoperative PainSpinal Cord StimulationUltrasound

Identifiers

PMID33155049
PMCPMC7971473
OpenAlexW3097466683

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.