Evidence map›Paper›PMID 33154994›Full record

ArticleRadiology. Cardiothoracic imaging2020

Accelerated 3D Left Atrial Late Gadolinium Enhancement in Patients with Atrial Fibrillation at 1.5 T: Technical Development.

Suvai Gunasekaran, Hassan Haji-Valizadeh, Daniel C Lee, Ryan J Avery, Brent D Wilson, Mark Ibrahim, Michael Markl, Rod S Passman, Eugene G Kholmovski, Daniel Kim

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Radiology. Cardiothoracic imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Suvai GunasekaranDepartment of Radiology (S.G., D.C.L., R.J.A., M.M., D.K.) and Department of Internal Medicine, Division of Cardiology (D.C.L., R.S.P.), Northwestern University Feinberg School of Medicine, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611; Department of Biomedical Engineering, Northwestern University, Evanston, Ill (S.G., M.M., D.K.); Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (H.H.V.); and Department of Internal Medicine, Division of Cardiovascular Medicine (B.D.W., M.I.), and Department of Radiology and Imaging Sciences (E.G.K.), University of Utah, Salt Lake City, Utah.
Hassan Haji-ValizadehDepartment of Radiology (S.G., D.C.L., R.J.A., M.M., D.K.) and Department of Internal Medicine, Division of Cardiology (D.C.L., R.S.P.), Northwestern University Feinberg School of Medicine, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611; Department of Biomedical Engineering, Northwestern University, Evanston, Ill (S.G., M.M., D.K.); Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (H.H.V.); and Department of Internal Medicine, Division of Cardiovascular Medicine (B.D.W., M.I.), and Department of Radiology and Imaging Sciences (E.G.K.), University of Utah, Salt Lake City, Utah.
Daniel C LeeDepartment of Radiology (S.G., D.C.L., R.J.A., M.M., D.K.) and Department of Internal Medicine, Division of Cardiology (D.C.L., R.S.P.), Northwestern University Feinberg School of Medicine, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611; Department of Biomedical Engineering, Northwestern University, Evanston, Ill (S.G., M.M., D.K.); Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (H.H.V.); and Department of Internal Medicine, Division of Cardiovascular Medicine (B.D.W., M.I.), and Department of Radiology and Imaging Sciences (E.G.K.), University of Utah, Salt Lake City, Utah.ORCID https://orcid.org/0000-0001-9447-4175
Ryan J AveryDepartment of Radiology (S.G., D.C.L., R.J.A., M.M., D.K.) and Department of Internal Medicine, Division of Cardiology (D.C.L., R.S.P.), Northwestern University Feinberg School of Medicine, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611; Department of Biomedical Engineering, Northwestern University, Evanston, Ill (S.G., M.M., D.K.); Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (H.H.V.); and Department of Internal Medicine, Division of Cardiovascular Medicine (B.D.W., M.I.), and Department of Radiology and Imaging Sciences (E.G.K.), University of Utah, Salt Lake City, Utah.ORCID https://orcid.org/0000-0002-7913-0574
Brent D WilsonDepartment of Radiology (S.G., D.C.L., R.J.A., M.M., D.K.) and Department of Internal Medicine, Division of Cardiology (D.C.L., R.S.P.), Northwestern University Feinberg School of Medicine, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611; Department of Biomedical Engineering, Northwestern University, Evanston, Ill (S.G., M.M., D.K.); Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (H.H.V.); and Department of Internal Medicine, Division of Cardiovascular Medicine (B.D.W., M.I.), and Department of Radiology and Imaging Sciences (E.G.K.), University of Utah, Salt Lake City, Utah.
Mark IbrahimDepartment of Radiology (S.G., D.C.L., R.J.A., M.M., D.K.) and Department of Internal Medicine, Division of Cardiology (D.C.L., R.S.P.), Northwestern University Feinberg School of Medicine, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611; Department of Biomedical Engineering, Northwestern University, Evanston, Ill (S.G., M.M., D.K.); Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (H.H.V.); and Department of Internal Medicine, Division of Cardiovascular Medicine (B.D.W., M.I.), and Department of Radiology and Imaging Sciences (E.G.K.), University of Utah, Salt Lake City, Utah.
Michael MarklDepartment of Radiology (S.G., D.C.L., R.J.A., M.M., D.K.) and Department of Internal Medicine, Division of Cardiology (D.C.L., R.S.P.), Northwestern University Feinberg School of Medicine, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611; Department of Biomedical Engineering, Northwestern University, Evanston, Ill (S.G., M.M., D.K.); Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (H.H.V.); and Department of Internal Medicine, Division of Cardiovascular Medicine (B.D.W., M.I.), and Department of Radiology and Imaging Sciences (E.G.K.), University of Utah, Salt Lake City, Utah.ORCID https://orcid.org/0000-0002-7686-1128
Rod S PassmanDepartment of Radiology (S.G., D.C.L., R.J.A., M.M., D.K.) and Department of Internal Medicine, Division of Cardiology (D.C.L., R.S.P.), Northwestern University Feinberg School of Medicine, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611; Department of Biomedical Engineering, Northwestern University, Evanston, Ill (S.G., M.M., D.K.); Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (H.H.V.); and Department of Internal Medicine, Division of Cardiovascular Medicine (B.D.W., M.I.), and Department of Radiology and Imaging Sciences (E.G.K.), University of Utah, Salt Lake City, Utah.
Eugene G KholmovskiDepartment of Radiology (S.G., D.C.L., R.J.A., M.M., D.K.) and Department of Internal Medicine, Division of Cardiology (D.C.L., R.S.P.), Northwestern University Feinberg School of Medicine, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611; Department of Biomedical Engineering, Northwestern University, Evanston, Ill (S.G., M.M., D.K.); Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (H.H.V.); and Department of Internal Medicine, Division of Cardiovascular Medicine (B.D.W., M.I.), and Department of Radiology and Imaging Sciences (E.G.K.), University of Utah, Salt Lake City, Utah.ORCID https://orcid.org/0000-0002-3271-7247
Daniel KimDepartment of Radiology (S.G., D.C.L., R.J.A., M.M., D.K.) and Department of Internal Medicine, Division of Cardiology (D.C.L., R.S.P.), Northwestern University Feinberg School of Medicine, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611; Department of Biomedical Engineering, Northwestern University, Evanston, Ill (S.G., M.M., D.K.); Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (H.H.V.); and Department of Internal Medicine, Division of Cardiovascular Medicine (B.D.W., M.I.), and Department of Radiology and Imaging Sciences (E.G.K.), University of Utah, Salt Lake City, Utah.ORCID https://orcid.org/0000-0003-2660-8973
Northwestern University · US

Funding

Precision MRI of Left Atrial Fibrosis for Patients with Atrial FibrillationR01HL116895 · NHLBI · UNIVERSITY OF UTAH · PI KIM, DANIEL · 2014 to 2025
$5.1M
Wideband 3D LGE and Coronary MRA for Planning Ventricular Tachycardia AblationR01HL151079 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Daniel Kim, Daniel Ching-Hao Lee · 2020 to 2026
$4.0M
Rapid Real-Time Cardiovascular MRI for Detecting Coronary Artery DiseaseR01HL138578 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KIM, DANIEL, LEE, DANIEL CHING-HAO · 2017 to 2019
$1.1M
Rapid Pediatric Cardiovascular MRI without Contrast Agent or AnesthesiaR21EB024315 · NIBIB · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KIM, DANIEL · 2017 to 2018
$567k
MRI of Left Atrial Hemodynamic Disorders in Atrial FibrillationR21AG055954 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KIM, DANIEL, MARKL, MICHAEL · 2017 to 2018
$487k
NHLBI NIH HHS R01 HL116895NHLBI NIH HHS R01 HL138578NHLBI NIH HHS R01 HL151079NIA NIH HHS R21 AG055954NIBIB NIH HHS R21 EB024315
6 · The paper itself

Abstract

purposeTo develop an accelerated three-dimensional (3D) late gadolinium enhancement (LGE) pulse sequence using balanced steady-state free precession readout with stack-of-stars k-space sampling and extra motion-state golden-angle radial sparse parallel (XD-GRASP) reconstruction and test the performance for detecting atrial scar and fibrosis in patients with atrial fibrillation (AF). MATERIALS AND

methodsTwenty-five patients with AF (20 paroxysmal and five persistent; 65 years ± 7 [standard deviation]; 18 men) were imaged at 1.5 T using the proposed LGE sequence with 1.3 mm × 1.3 mm × 2-mm spatial resolution and predictable imaging time. The resulting images were compared with historic images of 25 patients with AF (18 paroxysmal and seven persistent; 67 years ± 10; 14 men) obtained using a reference 3D left atrial (LA) LGE sequence with 1.3 mm × 1.3 mm × 2.5-mm spatial resolution. Two readers visually graded the 3D LGE images (conspicuity, artifact, noise) on a five-point Likert scale (1 = worst, 3 = acceptable, 5 = best), in which the summed visual score (SVS) of 9 or greater was defined as clinically acceptable. Appropriate statistical analyses (Cohen κ coefficient, Mann-Whitney

resultsMean imaging time was significantly shorter (

conclusionThe proposed 3D LA LGE method produced clinically acceptable image quality with 1.5 mm × 1.5 mm × 2-mm nominal spatial resolution and 6-minute predictable imaging time for quantification of LA scar and fibrosis in patients with AF.

Identifiers

PMID33154994
PMCPMC7605361
OpenAlexW3093156232

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.