ArticleFrontiers in cell and developmental biology2020
The Physical Role of Mesenchymal Cells Driven by the Actin Cytoskeleton Is Essential for the Orientation of Collagen Fibrils in Zebrafish Fins.
Article in Frontiers in cell and developmental biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 16 citations in OpenAlex.
- A collagen orientation switch reshapes fin architecture.iScience · 2026Article
- Actinotrichia-independent developmental mechanisms of spiny rays facilitate the morphological diversification of Acanthomorpha fish fins.Nature communications · 2026Article
- Trade-off between branching and polarity controls decision-making during cell migration.Science advances · 2026Article
- Exploration of phosphoproteomic association during epimorphic regeneration.Scientific reports · 2025Article
- Dynamics of actinotrichia, fibrous collagen structures in zebrafish fin tissues, unveiled by novel fluorescent probes.PNAS nexus · 2024Article
- Collagen9a1c localizes to collagen fibers called actinotrichia in zebrafish fins.microPublication biology · 2023Article
- Developmental independence of median fins from the larval fin fold revises their evolutionary origin.Scientific reports · 2022Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
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Abstract
Fibrous collagen imparts physical strength and flexibility to tissues by forming huge complexes. The density and orientation of collagen fibers must be correctly specified for the optimal physical property of the collagen complex. However, little is known about its underlying cellular mechanisms. Actinotrichia are collagen fibers aligned at the fin-tip of bony fish and are easily visible under the microscope due to their thick, linear structure. We used the actinotrichia as a model system to investigate how cells manipulate collagen fibers. The 3D image obtained by focused ion beam scanning electron microscopy (FIB-SEM) showed that the pseudopodia of mesenchymal cells encircle the multiple actinotrichia. We then co-incubated the mesenchymal cells and actinotrichia
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