Evidence map›Paper›PMID 33154968›Full record

ArticleFrontiers in cell and developmental biology2020

Cellular Changes in Retinas From Patients With

Vera L Bonilha, Brent A Bell, Meghan J DeBenedictis, Stephanie A Hagstrom, Gerald A Fishman, Joe G Hollyfield

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Clic6 Deficiency Triggers Aberrant Apical Microvilli in RPE.Investigative ophthalmology & visual science · 2025
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 1 country.

Vera L BonilhaDepartment of Ophthalmic Research, Cole Eye Institute, Cleveland Clinic, Cleveland, OH, United States.
Brent A BellDepartment of Ophthalmic Research, Cole Eye Institute, Cleveland Clinic, Cleveland, OH, United States.
Meghan J DeBenedictisDepartment of Ophthalmic Research, Cole Eye Institute, Cleveland Clinic, Cleveland, OH, United States.
Stephanie A HagstromDepartment of Ophthalmic Research, Cole Eye Institute, Cleveland Clinic, Cleveland, OH, United States.
Gerald A FishmanPangere Center at The Chicago Lighthouse for People Who Are Blind or Visually Impaired, Chicago, IL, United States.
Joe G HollyfieldDepartment of Ophthalmic Research, Cole Eye Institute, Cleveland Clinic, Cleveland, OH, United States.
Case Western Reserve University · USChicago Public Library · USCleveland Clinic · USCleveland Clinic Lerner College of Medicine · USCleveland Eye Clinic · USUniversity of Pennsylvania · US

Funding

RESOURCE/SERVICE CORE C - MOLECULAR INFORMATICS MODULEP30EY025585 · NEI · CLEVELAND CLINIC LERNER COM-CWRU · PI BELA ANAND-APTE · 2016 to 2026
$7.7M
RPE, aging and age-related macular degeneration: the role of oxidative stressR01EY027750 · NEI · CLEVELAND CLINIC LERNER COM-CWRU · PI BONILHA, VERA L · 2017 to 2021
$2.0M
NEI NIH HHS P30 EY025585NEI NIH HHS R01 EY027750
6 · The paper itself

Abstract

Best disease (BD), also known as vitelliform macular dystrophy, is an inherited disease of the central retina caused by more than 300 pathogenic variants in the

Indexed as

BEST1 genebest diseasehistopathologyphotoreceptorsretinal pigment epithelium

Identifiers

PMID33154968
PMCPMC7591587
OpenAlexW3093313749

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.