ArticleCurrent behavioral neuroscience reports2016
Developmental Neuroimaging in Pediatric Obsessive-Compulsive Disorder.
Article in Current behavioral neuroscience reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 8 citations in OpenAlex.
- Sex-specific alterations of intrinsic brain activity and functional connectivity in adolescent obsessive-compulsive disorder.Medical & biological engineering & computing · 2026Article
- Distinct neural substrates of obsessions and compulsions in adolescent obsessive compulsive disorder.Translational psychiatry · 2026Article
- Mechanisms of Change in Exposure Therapy for Anxiety and Related Disorders: A Research Agenda.Clinical psychological science : a journal of the Association for Psychological Science · 2025Article
- SAPAP3, SPRED2, and obsessive-compulsive disorder: the search for fundamental phenotypes.Frontiers in molecular neuroscience · 2023Article
- Neurochemical properties measured byJournal of neural transmission (Vienna, Austria : 1996) · 2021Article
- Obsessive-Compulsive Symptoms Among Children in the Adolescent Brain and Cognitive Development Study: Clinical, Cognitive, and Brain Connectivity Correlates.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2021Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
purpose of reviewThis review examines emerging neuroimaging research in pediatric obsessive compulsive disorder (OCD) and explores the possibility that developmentally sensitive mechanisms may underlie OCD across the lifespan. RECENT
findingsDiffusion tensor imaging (DTI) studies of pediatric OCD reveal abnormal structural connectivity within frontal-striato-thalamic circuity (FSTC). Resting-state functional magnetic resonance imaging (fMRI) studies further support atypical FSTC connectivity in young patients, but also suggest altered connectivity within cortical networks for task-control. Task-based fMRI studies show that hyper- and hypo-activation of task control networks may depend on task difficulty in pediatric patients similar to recent findings in adults. SUMMARY: This review suggests that atypical neurodevelopmental trajectories may underlie the emergence and early course of OCD. Abnormalities of structural and functional connectivity may vary with age, while functional engagement during task may vary with age and task complexity. Future research should combine DTI, resting-state fMRI and task-based fMRI methods and incorporate longitudinal designs to reveal developmentally sensitive targets for intervention.
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Registered trials
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