Evidence map›Paper›PMID 33154765›Full record

ArticleOncology letters2020

Long non-coding RNA MIAT promotes gastric cancer proliferation and metastasis via modulating the miR-331-3p/RAB5B pathway.

Xiao-Mei Li, Yan-Yan Jiao, Bao-Hong Luan, Hong-Xia Wu, Rong-Rong Wang, Jie Zhong

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xiao-Mei LiDepartment of Oncology, Qing Dao Cheng Yang People's Hospital, Qingdao, Shandong 266109, P.R. China.
Yan-Yan JiaoDepartment of Oncology, Qing Dao Cheng Yang People's Hospital, Qingdao, Shandong 266109, P.R. China.
Bao-Hong LuanDepartment of Oncology, Qing Dao Cheng Yang People's Hospital, Qingdao, Shandong 266109, P.R. China.
Hong-Xia WuDepartment of Oncology, Qing Dao Cheng Yang People's Hospital, Qingdao, Shandong 266109, P.R. China.
Rong-Rong WangDepartment of Oncology, Qing Dao Cheng Yang People's Hospital, Qingdao, Shandong 266109, P.R. China.
Jie ZhongDepartment of Interventional Radiography, Qing Dao Cheng Yang People's Hospital, Qingdao, Shandong 266109, P.R. China.
Qingdao Eighth People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer (GC) remains a threat to the health of the global population. The present study investigated the effects and mechanisms of the long non-coding RNA myocardial infarction associated transcript (MIAT) on the proliferation, apoptosis and metastasis of GC (HGC-27 and AGS) cells. The expression levels of MIAT, micoRNA (miR)-331-3p and RAB5B mRNA were analyzed using reverse transcription-quantitative PCR analysis. Cell growth, apoptosis, migration and invasion were measured using 5-ethynyl-2'-deoxyuridine, flow cytometry, wound healing and Transwell assays, respectively. A luciferase assay was used to determine whether miR-331-3p targeted MIAT and RAB5B. The results indicated that MIAT levels

Indexed as

gastric cancerlong non-coding RNA MIATmicroRNA-331-3pRas-related protein Rab-5B

Identifiers

PMID33154765
PMCPMC7608069
OpenAlexW3093283000

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.