Evidence map›Paper›PMID 33154752›Full record

ArticleFrontiers in immunology2020

Increased Hydrostatic Pressure Promotes Primary M1 Reaction and Secondary M2 Polarization in Macrophages.

Bo Wang, Maren Kasper, Björn Laffer, Gerd Meyer Zu Hörste, Susanne Wasmuth, Martin Busch, Tida Viola Jalilvand, Solon Thanos, Arnd Heiligenhaus, Dirk Bauer and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Immune responses to injury and their links to eye disease.Translational research : the journal of laboratory and clinical medicine · 2021
    Review
  8. Glycoproteins FromFrontiers in pharmacology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Bo WangOphthalmology and Ophtha-Lab at St. Franziskus Hospital, Münster, Germany.
Maren KasperOphthalmology and Ophtha-Lab at St. Franziskus Hospital, Münster, Germany.
Björn LafferOphthalmology and Ophtha-Lab at St. Franziskus Hospital, Münster, Germany.
Gerd Meyer Zu HörsteInstitution of Neurology and Institution for Translational Neurology, Universitätsklinikum Münster, Münster, Germany.
Susanne WasmuthOphthalmology and Ophtha-Lab at St. Franziskus Hospital, Münster, Germany.
Martin BuschOphthalmology and Ophtha-Lab at St. Franziskus Hospital, Münster, Germany.
Tida Viola JalilvandOphthalmology and Ophtha-Lab at St. Franziskus Hospital, Münster, Germany.
Solon ThanosInstitution of Experimental Ophthalmology, Westfälische Wilhelms-Universität, Münster, Germany.
Arnd HeiligenhausOphthalmology and Ophtha-Lab at St. Franziskus Hospital, Münster, Germany.
Dirk BauerOphthalmology and Ophtha-Lab at St. Franziskus Hospital, Münster, Germany.
Carsten HeinzOphthalmology and Ophtha-Lab at St. Franziskus Hospital, Münster, Germany.
St. Franziskus Hospital · DEUniversity Hospital Münster · DEUniversity of Duisburg-Essen · DEUniversity of Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with chronic anterior uveitis are at particularly high risk of developing secondary glaucoma when corticosteroids [e.g., dexamethasone (Dex)] are used or when inflammatory activity has regressed. Macrophage migration into the eye increases when secondary glaucoma develops and may play an important role in the development of secondary glaucoma. Our aim was to evaluate

Indexed as

AnimalsCells, CulturedCell SurvivalCollagen Type IVDexamethasoneExtracellular MatrixFibronectinsGlaucomaHydrostatic PressureInflammationInterleukin-10LipopolysaccharidesMacrophagesMicePhenotypeTumor Necrosis Factor-alphaCollagen Type IVDexamethasoneFibronectinsInterleukin-10LipopolysaccharidesTumor Necrosis Factor-alphadexamethasone (DEX)ECM-extracellular matrixincreased hydrostatic pressureM1/M2 balancemacrophagesecondary glaucoma

Identifiers

PMID33154752
PMCPMC7591771
OpenAlexW3093418062

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.