ArticleJournal of pain research2020
Favorite Music Mediates Pain-related Responses in the Anterior Cingulate Cortex and Skin Pain Thresholds.
Article in Journal of pain research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Does music counteract mental fatigue? A systematic review.PloS one · 2025Pooled it
- A scoping review of music-based pain treatment mechanism research.Pain reports · 2026Review
- A primary auditory cortex-anterior cingulate cortex circuit underlying cross-modal visceral pain modulation.Nature communications · 2026Article
- A Comprehensive Review of the Clinical Utility and Reliability of a Quantitative Electrical Stimulation Device for Objective Pain Assessment.Journal of pain research · 2026Review
- Proposed Physiological and Neurobiological Mechanisms of Music's Effect, with a Focus on the Perioperative Period: Literature Evidence from Human, Canine and Feline Medicine.Veterinary sciences · 2025Review
- Functional Impact of Increasing Minor Intervals in North Indian Classical Music on Cortical Sources and Emotional Responses.Annals of neurosciences · 2025Article
- Implications for the Ergogenic Benefits of Self-Selected Music in Neurological Conditions: A Theoretical Review.Neurology international · 2025Review
- A multidisciplinary approach on music induced-analgesia differentiated by socio-cultural background in healthy volunteers (MOSART): A cross-over randomized controlled trial protocol.Contemporary clinical trials communications · 2024Article
- The psychophysiology of music-based interventions and the experience of pain.Frontiers in psychology · 2024Review
- Pain is what you think: functional magnetic resonance imaging evidence toward a cognitive and affective approach for pain research.Frontiers in pain research (Lausanne, Switzerland) · 2024Article
- Multimodal non-invasive non-pharmacological therapies for chronic pain: mechanisms and progress.BMC medicine · 2023Review
- Exploring the Synergy of Music and Medicine in Healthcare: Expert Insights into the Curative and Societal Role of the Relationship between Music and Medicine.International journal of environmental research and public health · 2023Article
- The effect of background liked music on acute pain perception and its neural correlates.Human brain mapping · 2023Article
- Emotional responses to favorite and relaxing music predict music-induced hypoalgesia.Frontiers in pain research (Lausanne, Switzerland) · 2023Article
- State-of-the-Art Review on Immersive Virtual Reality Interventions for Colonoscopy-Induced Anxiety and Pain.Journal of clinical medicine · 2022Review
- Music to My Senses: Functional Magnetic Resonance Imaging Evidence of Music Analgesia Across Connectivity Networks Spanning the Brain and Brainstem.Frontiers in pain research (Lausanne, Switzerland) · 2022Article
- Music-Induced Analgesia in Healthy Participants Is Associated With Expected Pain Levels but Not Opioid or Dopamine-Dependent Mechanisms.Frontiers in pain research (Lausanne, Switzerland) · 2022Article
- The Influence of Music Preference on Exercise Responses and Performance: A Review.Journal of functional morphology and kinesiology · 2021Review
- Effect of Music Therapy on Postoperative Pain Management in Patients with Oral Cancer: A Retrospective Study.Noise & healthArticle
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeMusic therapy is widely used to enhance well-being, reduce pain, and distract patients from unpleasant symptoms in the clinical setting. However, the degree to which music modulates pain perception is unknown. The medial pain pathway including the limbic system is associated with emotion, but how music alters pathway activity is unclear. The aim of the study was to investigate pain thresholds and pain-related responses in the anterior cingulate cortex (ACC) and whether they were modulated when subjects listened to their favorite music genre. SUBJECTS AND
methodsFirst, 30 subjects were examined for left forearm pain threshold using electrical stimulation with Pain Vision PS-2011N. The pain thresholds with and without music were compared. Second, when an 80-μA current from Pain Vision was applied to the left ankle of eight women, the pain-related responses of the ACC with and without music were observed with functional magnetic resonance device (fMRI). The changes in the pain-related activity in both parameters were discussed.
resultsThe median pain threshold with favorite music was 38.9 μA, compared to 29.0 μA without, which was significantly different (
conclusionThe present findings suggest that pain perception might be strongly affected by listening to favorite music, possibly through modulation of pain-related responses in the ACC.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.