Evidence map›Paper›PMID 33154483›Full record

ArticleScientific reports2020

Palmitate and pyruvate carbon flux in response to choline and methionine in bovine neonatal hepatocytes.

T L Chandler, S J Erb, William A Myers, Pragney Deme, Norman J Haughey, J W McFadden, H M White

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

T L ChandlerDepartment of Dairy Science, University of Wisconsin-Madison, Madison, WI, 53706, USA.
S J ErbDepartment of Dairy Science, University of Wisconsin-Madison, Madison, WI, 53706, USA.
William A MyersDepartment of Animal Science, Cornell University, Ithaca, NY, 14853, USA.
Pragney DemeDivision of Neuroimmunology and Neurological Infections, Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.
Norman J HaugheyDivision of Neuroimmunology and Neurological Infections, Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.
J W McFaddenDepartment of Animal Science, Cornell University, Ithaca, NY, 14853, USA.
H M WhiteDepartment of Dairy Science, University of Wisconsin-Madison, Madison, WI, 53706, USA. heather.white@wisc.edu.
Cornell University · USJohns Hopkins Medicine · USUniversity of Wisconsin–Madison · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Choline and methionine may serve unique functions to alter hepatic energy metabolism. Our objective was to trace carbon flux through pathways of oxidation and glucose metabolism in bovine hepatocytes exposed to increasing concentrations of choline chloride (CC) and D,L-methionine (DLM). Primary hepatocytes were isolated from 4 Holstein calves and maintained for 24 h before treatment with CC (0, 10, 100, 1000 μmol/L) and DLM (0, 100, 300 μmol/L) in a factorial design. After 21 h, [1-

Indexed as

AnimalsAnimals, NewbornCarbon CycleCattleCells, CulturedCholineEnergy MetabolismFatty AcidsGlucoseHepatocytesLipid MetabolismMaleMethionineOxidation-ReductionOxidative StressPalmitatesCholineFatty AcidsGlucoseMethioninePalmitatesPyruvic AcidReactive Oxygen SpeciesTriglycerides

Identifiers

PMID33154483
PMCPMC7645801
OpenAlexW3094977074

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.