Evidence map›Paper›PMID 33154477›Full record

ArticleScientific reports2020

HDL cholesterol efflux capacity is inversely associated with subclinical cardiovascular risk markers in young adults: The cardiovascular risk in Young Finns study.

Monika Hunjadi, Claudia Lamina, Patrick Kahler, Tamara Bernscherer, Jorma Viikari, Terho Lehtimäki, Mika Kähönen, Mikko Hurme, Markus Juonala, Leena Taittonen and 6 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 34 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. HDL Is Not Dead Yet.Biomedicines · 2022
    Review
  12. Article
  13. Article
  14. Cancers · 2021
    Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 10 institutions in 2 countries.

Monika HunjadiDepartment of Internal Medicine I, Medical University of Innsbruck, Anichstraße 35, 6020, Innsbruck, Austria. monika.hunjadi@alumni.i-med.ac.at.
Claudia LaminaDivision of Genetic Epidemiology, Medical University of Innsbruck, Innsbruck, Austria.
Patrick KahlerDepartment of Internal Medicine I, Medical University of Innsbruck, Anichstraße 35, 6020, Innsbruck, Austria.
Tamara BernschererDepartment of Internal Medicine I, Medical University of Innsbruck, Anichstraße 35, 6020, Innsbruck, Austria.
Jorma ViikariDepartment of Medicine, University of Turku and Division of Medicine, Turku University Hospital, Turku, Finland.
Terho LehtimäkiDepartment of Clinical Chemistry, Fimlab Laboratories and Finnish Cardiovascular Research Center-Tampere Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Mika KähönenDepartment of Clinical Physiology, Tampere University Hospital and Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Mikko HurmeDepartment of Microbiology and Immunology, Faculty of Medicine and Health Technology, Tampere University and Pirkanmaa Hospital District, Tampere, Finland.
Markus JuonalaDepartment of Medicine, University of Turku and Division of Medicine, Turku University Hospital, Turku, Finland.
Leena TaittonenVaasa Central Hospital, Vaasa, Finland.
Tomi LaitinenDepartment of Clinical Physiology and Nuclear Medicine, Kuopio, University Hospital and University of Eastern Finland, Kuopio, Finland.
Eero JokinenDepartment of Pediatric Cardiology, Hospital for Children and Adolescents, University of Helsinki, Helsinki, Finland.
Päivi TossavainenDepartment of Pediatrics, Oulu University Hospital, PEDEGO Research Unit and MRC Oulu, University of Oulu, Oulu, Finland.
Nina Hutri-KähönenDepartment of Clinical Physiology, Tampere University Hospital and Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Olli RaitakariResearch Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.
Andreas RitschDepartment of Internal Medicine I, Medical University of Innsbruck, Anichstraße 35, 6020, Innsbruck, Austria.
Innsbruck Medical University · ATTampere University · FITampere University Hospital · FITurku University Hospital · FIUniversität Innsbruck · ATKuopio University Hospital · FIOulu University Hospital · FIUniversity of Helsinki · FIUniversity of Turku · FIVaasa Central Hospital · FI

Funding

Austrian Science Fund FWF P 27116Austrian Science Fund FWF P27116-B23 to AREuropean Research Council 742927 for MULTIEPIGEN project
6 · The paper itself

Abstract

The atherogenic process begins already in childhood and progresses to symptomatic condition with age. We investigated the association of cholesterol efflux capacity (CEC) and vascular markers of subclinical atherosclerosis in healthy, young adults. CEC was determined in 2282 participants of the Young Finns study using cAMP treated

Indexed as

Heart Disease Risk FactorsAdultAtherosclerosisBiomarkersCardiovascular DiseasesCarotid ArteriesCarotid Intima-Media ThicknessCholesterol, HDLElastic ModulusFemaleFinlandFollow-Up StudiesHumansIncidenceMaleRisk AssessmentBiomarkersCholesterol, HDL

Identifiers

PMID33154477
PMCPMC7645719
OpenAlexW3097847916

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.