Evidence map›Paper›PMID 33154468›Full record

Observational studyScientific reports2020

Vitamin D and subclinical cardiac damage in a cohort of kidney transplanted patients: a retrospective observational study.

C Alfieri, S Vettoretti, O Ruzhytska, M T Gandolfo, D Cresseri, M Campise, L Caldiroli, E Favi, V Binda, P Messa

Abstract readObservational Study
In one paragraph

Observational study in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

C AlfieriNephrology, Dialysis and Renal Transplantation, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico - Milano, Via Commenda 15, 20122, Milan, Italy.
S VettorettiNephrology, Dialysis and Renal Transplantation, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico - Milano, Via Commenda 15, 20122, Milan, Italy.
O RuzhytskaNephrology, Dialysis and Renal Transplantation, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico - Milano, Via Commenda 15, 20122, Milan, Italy.
M T GandolfoNephrology, Dialysis and Renal Transplantation, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico - Milano, Via Commenda 15, 20122, Milan, Italy.
D CresseriNephrology, Dialysis and Renal Transplantation, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico - Milano, Via Commenda 15, 20122, Milan, Italy.
M CampiseNephrology, Dialysis and Renal Transplantation, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico - Milano, Via Commenda 15, 20122, Milan, Italy.
L CaldiroliNephrology, Dialysis and Renal Transplantation, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico - Milano, Via Commenda 15, 20122, Milan, Italy.
E FaviDepartment of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
V BindaNephrology, Dialysis and Renal Transplantation, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico - Milano, Via Commenda 15, 20122, Milan, Italy.
P MessaNephrology, Dialysis and Renal Transplantation, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico - Milano, Via Commenda 15, 20122, Milan, Italy. piergiorgio.messa@unimi.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In 178-kidney transplanted patients (KTxp), the prevalence of hypovitaminosis-D, the presence and novel development of left ventricular hypertrophy(LVH) and the correlations between native Vitamin-D (25OHD) and LVH were evaluated during the 1st year of transplantation (KTx). Clinical and instrumental data were recorded at pre-KTx and at one (T1) and 12 (T12) months after KTx. 25OHD levels were considered sufficient (s25OHD, ≥ 30 ng/dL) or insufficient (i25OHD, < 30 ng/dL). 25OHD correlated at T1 with parathormone(PTH), and at T12 with 25OHD-T1 and PTH-(T1,T12). At T12, s25OHD (15%) had higher 25OH and alkaline phosphatase (ALP), lower Ca, at T1, and lower PTH-(T1, T12) than i25OH-T12. At T1, KTxp with LVH (LVH-T1pos, 42%) were older and with longer dialysis vintage than LVH-T1neg. At T12, KTxp with LVH (LVH-T12pos, 53%) were older, with higher systolic blood pressure (SBP) at T12 than LVH-T12neg. No relation between 25OHD and LVH were found. Novel LVH was found in 14% of KTxp. They were older, had higher SBP-T12 and lower serum albumin-T12 than the others. LVH-modifications and 25OHD were not correlated. Hypovitaminosis-D is highly prevalent in KTxp. LVH correlates with different risk factors according to the time elapsed from KTx. However, during the 1st year of KTx, no relationship between LVH and 25OHD was observed.

Indexed as

Kidney TransplantationTransplant RecipientsAdultAge FactorsAlkaline PhosphataseCalciumFemaleHumansHypertrophy, Left VentricularMaleMiddle AgedParathyroid HormonePrevalenceRetrospective StudiesSerum AlbuminVitamin DAlkaline PhosphataseCalciumParathyroid HormoneSerum AlbuminVitamin D

Identifiers

PMID33154468
PMCPMC7645736

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.