Evidence map›Paper›PMID 33154429›Full record

ArticleScientific reports2020

Electronic health record alerts enhance mass screening for chronic hepatitis B.

Eric Chak, Chin-Shang Li, Moon S Chen, Scott MacDonald, Christopher Bowlus

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04240678 (The Effect of an Electronic Medical Record), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04240678 nacompletednot on this map

The Effect of an Electronic Medical Record (EMR) Alert on Hepatitis B Screening: A Randomized Controlled Trial

TypeinterventionalSponsorUniversity of California, DavisRan2016 to 2021Enrolled8,299ConditionsHepatitis BArmsElectronic HBV Alert
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Eric ChakDivision of Gastroenterology and Hepatology, UC Davis School of Medicine, 4150 V Street, PSSB 3500, Sacramento, CA, USA. echak@ucdavis.edu.
Chin-Shang LiSchool of Nursing, The State University of New York, University at Buffalo, Buffalo, NY, USA.
Moon S ChenDivision of Hematology and Oncology, UC Davis School of Medicine, Sacramento, CA, USA.
Scott MacDonaldDivision of Clinical Informatics, UC Davis Medical Center, Sacramento, CA, USA.
Christopher BowlusDivision of Gastroenterology and Hepatology, UC Davis School of Medicine, 4150 V Street, PSSB 3500, Sacramento, CA, USA.
University of California, Davis · USNew York University · USUniversity of California Davis Medical Center · US

Funding

UC Davis Clinical and Translational Science CenterUL1TR001860 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KENYON, NICHOLAS J., LYLES, COURTNEY REES · 2016 to 2025
$47.3M
SACRAMENTO COLLABORATIVE TO ADVANCE TESTING AND CARE OF HEPATITIS B (SCRATCH)U51PS004633 · PS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BOWLUS, CHRISTOPHER L. · 2014 to 2015
$627k
CDC HHS 1U51PS004633-01NCATS NIH HHS UL1 TR001860NCATS NIH HHS UL1TR001860NCHHSTP CDC HHS U51 PS004633
6 · The paper itself

Abstract

To measure the effect of an electronic health record (EHR) alert on chronic hepatitis B (CHB) screening among at-risk Asian and Pacific Islanders (API). API patients who had not yet completed hepatitis B surface antigen (HBsAg) testing were identified by a novel EHR-based population health tool. At-risk API patients in Cohort 1 (primarily privately insured) and Cohort 2 (includes Medicare and/or Medicaid) were randomized to alert activation in their electronic medical charts or not. In total, 8299 API were found to be deficient in HBsAg completion at baseline within our health system. In Cohort 1, 1542 patients and 1568 patients were randomized to the alert and control respectively. In Cohort 2, 2599 patients and 2590 patients were randomized to the alert and control respectively. For both cohorts combined, 389 HBsAg tests were completed in the alert group compared to 177 HBsAg tests in the control group (p < 0.0001; OR = 2.3; 95% CI 1.94-2.80), but there was no increased detection of HBsAg positivity from the alert (15 versus 13 respectively, p = 0.09; OR = 0.5; 95% CI 0.24-1.09). Our results demonstrate that personalized, automated electronic alerts increase screening for CHB, but more comprehensive measures are needed to detect HBsAg positive patients.NIH Trial Registry Number: NCT04240678.

Indexed as

Electronic Health RecordsAdolescentAdultAgedAged, 80 and overAsianCaliforniaFemaleHepatitis B, ChronicHumansMaleMass ScreeningMiddle AgedNative Hawaiian or Pacific IslanderYoung Adult

Identifiers

PMID33154429
PMCPMC7644717
OpenAlexW3096180244

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.