Evidence map›Paper›PMID 33153960›Full record

ArticleDiabetes research and clinical practice2020

The OGTT is highly reproducible in Africans for the diagnosis of diabetes: Implications for treatment and protocol design.

Ram Jagannathan, Christopher W DuBose, Lilian S Mabundo, Stephanie T Chung, Joon Ha, Arthur Sherman, Michael Bergman, Anne E Sumner

Registry-linked trialAbstract read
In one paragraph

Article in Diabetes research and clinical practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00001853 (Diabetes and Heart Disease Risk in Blacks), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00001853 recruitingnot on this map

Diabetes and Heart Disease Risk in Blacks

TypeobservationalSponsorNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Ran1998Enrolled2,000ConditionsCardiovascular Diseases, Diabetes, Obesity, Hypertension
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Article
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  12. Article
  13. Sleep and Economic Status Are Linked to Daily Life Stress in African-Born Blacks Living in America.International journal of environmental research and public health · 2022
    Article
  14. Article
  15. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ram JagannathanDepartment of Medicine, Emory University School of Medicine, Atlanta, Georgia, United States.
Christopher W DuBoseSection on Ethnicity and Health, Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, United States.
Lilian S MabundoSection on Ethnicity and Health, Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, United States.
Stephanie T ChungSection on Ethnicity and Health, Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, United States.
Joon HaLaboratory of Biological Modeling, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, United States.
Arthur ShermanLaboratory of Biological Modeling, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, United States.
Michael BergmanDivision of Endocrinology and Metabolism, Department of Medicine and of Population Health, New York University School of Medicine, New York, NY, United States.
Anne E SumnerSection on Ethnicity and Health, Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, United States; National Institute of Minority Health and Health Disparities, National Institutes of Health, Bethesda, MD, United States. Electronic address: annes@mail.nih.gov.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Whether an OGTT reproducibly detects either type 2 diabetes (T2D) or prediabetes in Africans in unknown. Therefore, 131 Africans had two OGTT. Diagnostic reproducibility for T2D was excellent (κ = 0.84), but only moderate for prediabetes (κ = 0.51). A single OGTT positive for T2D may be sufficient to guide clinical care and inform epidemiologic study design. ClinicalTrials.gov Identifier: NCT00001853.

Indexed as

AdultAfricaAgedBlood GlucoseDiabetes Mellitus, Type 2FemaleGlucose Tolerance TestHumansMaleMiddle AgedReproducibility of ResultsYoung AdultBlood GlucoseAfricansDiabetesFasting plasma glucoseOGTT

Identifiers

PMID33153960
PMCPMC7578647

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.