Evidence map›Paper›PMID 33153518›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2020

Point-of-care tests for influenza A and B viruses and RSV in emergency departments - indications, impact on patient management and possible gains by syndromic respiratory testing, Capital Region, Denmark, 2018.

Uffe Vest Schneider, Mona Katrine Alberthe Holm, Didi Bang, Randi Føns Petersen, Shila Mortensen, Ramona Trebbien, Jan Gorm Lisby

Abstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Factors associated with antibiotic prescription among patients with respiratory illness in Thailand: The potential impact of rapid influenza diagnostic testing in antimicrobial stewardship.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Point of care testing for infectious disease: ownership and quality.The Journal of antimicrobial chemotherapy · 2021
    Article
  12. The cat is out of the bag - point-of-care testing (POCT) is here to stay.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Uffe Vest SchneiderDepartment of Clinical Microbiology, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.
Mona Katrine Alberthe HolmDepartment of Clinical Microbiology, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.
Didi BangDepartment of Virus & Microbiological Special Diagnostics, Statens Serum Institut, Copenhagen, Denmark.
Randi Føns PetersenDepartment of Virus & Microbiological Special Diagnostics, Statens Serum Institut, Copenhagen, Denmark.
Shila MortensenDepartment of Virus & Microbiological Special Diagnostics, Statens Serum Institut, Copenhagen, Denmark.
Ramona TrebbienDepartment of Virus & Microbiological Special Diagnostics, Statens Serum Institut, Copenhagen, Denmark.
Jan Gorm LisbyDepartment of Clinical Microbiology, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundPoint-of-care tests (POCT) for influenza A and B viruses and respiratory syncytial virus (RSV) were implemented in emergency departments of all hospitals in the Capital Region of Denmark in 2018.AimTo establish whether POC testing for influenza viruses or RSV is based on a valid respiratory symptom indication, whether changes in patient management based on a positive result are safe and whether syndromic POC testing may benefit patients with influenza or RSV.MethodsSamples from 180 children (< 18 years) and 375 adults tested using POCT between February and July 2018 were retested for 26 respiratory pathogens. Diagnosis, indication for POC testing, hospitalisation time, antimicrobial therapy and readmission or death within one month of testing were obtained from patient records.ResultsA valid indication for POC testing was established in 168 (93.3%) of children and 334 (89.1%) of adults. A positive POCT result significantly reduced antibiotic prescription and median hospitalisation time by 44.3 hours for adults and 14.2 hours for children, and significantly increased antiviral treatment in adults. Risk of readmission or death was not significantly altered by a positive result. Testing for 26 respiratory pathogens established that risk of coinfection is lower with increasing age and that POCT for adults should be restricted to the influenza and RSV season.ConclusionPositive POCT resulted in changed patient management for both children and adults, and was deemed safe. POCT for additional pathogens may be beneficial in children below 5 years of age and outside the influenza and RSV season.

Indexed as

Emergency Service, HospitalInfluenza A virusInfluenza B virusInfluenza, HumanPoint-of-Care TestingRespiratory Syncytial VirusesRespiratory Syncytial Virus InfectionsAdolescentAdultAgedChildChild, PreschoolDenmarkFemaleHumansInfantbedside testingFilmArrayindicationinfluenza A and B viruses and RSVnear patient testingpatient managementpoint-of-careRoche cobas Liat systemsyndromic testing

Identifiers

PMID33153518
PMCPMC7645972

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.