Evidence map›Paper›PMID 33153403›Full record

ArticleAutophagy2020

Highlights in the fight against COVID-19: does autophagy play a role in SARS-CoV-2 infection?

Elizabeth Delorme-Axford, Daniel J Klionsky

Open access · bronzeAbstract readEditorial
In one paragraph

Article in Autophagy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
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  14. Moments in autophagy and disease: Past and present.Molecular aspects of medicine · 2021
    Review
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  16. Article
  17. Review
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  19. Article
  20. COVID-19-associated diarrhea.World journal of gastroenterology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Elizabeth Delorme-AxfordDepartment of Biological Sciences, Oakland University , Rochester, MI, USA.ORCID 0000-0002-7455-7616
Daniel J KlionskyLife Sciences Institute, University of Michigan , Ann Arbor, MI, USA.ORCID 0000-0002-7828-8118
Oakland University · USUniversity of Michigan · US

Funding

The mechanism and regulation of autophagyR35GM131919 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DANIEL J. KLIONSKY · 2019 to 2026
$6.4M
NIGMS NIH HHS R35 GM131919
6 · The paper itself

Abstract

In the preceding months, the novel SARS-CoV-2 pandemic has devastated global communities. The need for safe and effective prophylactic and therapeutic treatments to combat COVID-19 - the human disease resulting from SARS-CoV-2 infection - is clear. Here, we present recent developments in the effort to combat COVID-19 and consider whether SARS-CoV-2 may potentially interact with the host autophagy pathway.

Indexed as

Adenosine MonophosphateAlanineAnimalsAntibodies, MonoclonalAntimetabolitesAntiviral AgentsAutophagyBetacoronavirusCOVID-19DexamethasoneDisease OutbreaksDrug DevelopmentHumansMicePandemicsSARS-CoV-2Adenosine MonophosphateAlanineAntibodies, MonoclonalAntimetabolitesAntiviral AgentsDexamethasoneremdesivirACE2chloroquinedexamethasonehydroxychloroquineLC3macroautophagyremdesivirTMPRSS2

Identifiers

PMID33153403
PMCPMC7651184
OpenAlexW3097703718

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.