Evidence map›Paper›PMID 33153375›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2021

Impact of blood pressure changes in cerebral blood perfusion of patients with ischemic Moyamoya disease evaluated by SPECT.

Zhao Liming, Sun Weiliang, Jia Jia, Liang Hao, Liu Yang, Christopher Ludtka, Behnam Rezai Jahromi, Felix Goehre, Ajmal Zemmar, Li Tianxiao and 3 more

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In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Zhao LimingDepartment of Neurosurgery, Cerebrovascular Disease Hospital, Henan Provincial People's Hospital; Zhengzhou University, Zhengzhou, China.
Sun WeiliangDepartment of Neurosurgery, Cerebrovascular Disease Hospital, Henan Provincial People's Hospital; Zhengzhou University, Zhengzhou, China.
Jia JiaDepartment of Anesthesiology and Perioperative medicine, Henan Provincial People's Hospital; Zhengzhou; Zhengzhou, China.
Liang HaoDepartment of Neurosurgery, Cerebrovascular Disease Hospital, Henan Provincial People's Hospital; Zhengzhou University, Zhengzhou, China.
Liu YangDepartment of Neurosurgery, Cerebrovascular Disease Hospital, Henan Provincial People's Hospital; Zhengzhou University, Zhengzhou, China.
Christopher Ludtka"Juha Hernesniemi" International Center for Neurosurgery, Henan Provincial People's Hospital, Zhengzhou University, Zhengzhou, China.
Behnam Rezai JahromiDepartment of Neurosurgery, Cerebrovascular Disease Hospital, Henan Provincial People's Hospital; Zhengzhou University, Zhengzhou, China.ORCID 0000-0003-3937-2816
Felix GoehreDepartment of Neurosurgery, BG Klinikum Bergmannstrost Halle, Halle, Germany.
Ajmal ZemmarDepartment of Neurosurgery, Cerebrovascular Disease Hospital, Henan Provincial People's Hospital; Zhengzhou University, Zhengzhou, China.
Li TianxiaoDepartment of Neurosurgery, Cerebrovascular Disease Hospital, Henan Provincial People's Hospital; Zhengzhou University, Zhengzhou, China.
Juha HernesniemiDepartment of Neurosurgery, Cerebrovascular Disease Hospital, Henan Provincial People's Hospital; Zhengzhou University, Zhengzhou, China.
Hugo Andrade-BarazarteDepartment of Neurosurgery, Cerebrovascular Disease Hospital, Henan Provincial People's Hospital; Zhengzhou University, Zhengzhou, China.ORCID 0000-0001-6673-6369
Li ChaoyueDepartment of Neurosurgery, Cerebrovascular Disease Hospital, Henan Provincial People's Hospital; Zhengzhou University, Zhengzhou, China.
Zhengzhou University · CNBG Klinikum Bergmannstrost Halle · DEHenan Provincial People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our aim was to determine the impact of targeted blood pressure modifications on cerebral blood flow in ischemic moyamoya disease patients assessed by single-photon emission computed tomography (SPECT). From March to September 2018, we prospectively collected data of 154 moyamoya disease patients and selected 40 patients with ischemic moyamoya disease. All patients underwent in-hospital blood pressure monitoring to determine the mean arterial pressure baseline values. The study cohort was subdivided into two subgroups: (1) Group A or relative high blood pressure (RHBP) with an induced mean arterial pressure 10-20% higher than baseline and (2) Group B or relative low blood pressure (RLBP) including patients with mean arterial pressure 10-20% lower than baseline. All patients underwent initial SPECT study on admission-day, and on the following day, every subgroup underwent a second SPECT study under their respective targeted blood pressure values. In general, RHBP patients showed an increment in perfusion of 10.13% (SD 2.94%), whereas RLBP patients showed a reduction of perfusion of 12.19% (SD 2.68%). Cerebral blood flow of moyamoya disease patients is susceptible to small blood pressure changes, and cerebral autoregulation might be affected due to short dynamic blood pressure modifications.

Indexed as

AdolescentAdultBlood PressureCerebrovascular CirculationFemaleHumansMaleMiddle AgedMoyamoya DiseaseTomography, Emission-Computed, Single-PhotonYoung Adultblood pressurebrain imagingCerebral blood flowcerebral hemodynamicsmoyamoya disease

Identifiers

PMID33153375
PMCPMC8142135
OpenAlexW3096594868

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.