Evidence map›Paper›PMID 33153246›Full record

ArticleClinical endoscopy2020

Positive Fecal Occult Blood Test is a Predictive Factor for Gastrointestinal Bleeding after Capsule Endoscopy in Patients with Unexplained Iron Deficiency Anemia: A Korean Multicenter CAPENTRY Study.

Ji Young Chang, Chang Mo Moon, Ki-Nam Shim, Dae Young Cheung, Hyun Seok Lee, Yun Jeong Lim, Seong Ran Jeon, Soo Jung Park, Kyeong Ok Kim, Hyun Joo Song and 2 more

Open access · goldAbstract read
In one paragraph

Article in Clinical endoscopy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 10 institutions in 1 country.

Ji Young ChangDepartment of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Korea.
Chang Mo MoonDepartment of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Korea.
Ki-Nam ShimDepartment of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Korea.
Dae Young CheungDepartment of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea.
Hyun Seok LeeDepartment of Internal Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, Korea.
Yun Jeong LimDepartment of Internal Medicine, Dongguk University Ilsan Hospital, Goyang, Korea.
Seong Ran JeonDepartment of Internal Medicine, Soonchunhyang University College of Medicine, Seoul, Korea.
Soo Jung ParkDepartment of Internal Medicine and Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, Korea.
Kyeong Ok KimDepartment of Internal Medicine, Yeungnam University College of Medicine, Daegu, Korea.
Hyun Joo SongDepartment of Internal Medicine, Jeju National University School of Medicine, Jeju, Korea.
Hyun Joo JangDepartment of Internal Medicine, Hallym University College of Medicine, Hwasung, Korea.
Ji Hyun KimDepartment of Internal Medicine, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.
Ewha Womans University · KRCatholic University of Korea · KRDongguk University Ilsan Hospital · KRHallym University · KRInje University Busan Paik Hospital · KRJeju National University · KRKyungpook National University Hospital · KRSoonchunhyang University · KRYeungnam University CollegeYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsCapsule endoscopy (CE) is recommended as the primary method for the evaluation of unexplained anemia. This study aimed to assess the diagnostic yield of CE in patients with unexplained iron deficiency anemia (IDA) without overt bleeding, and to evaluate their long-term outcomes and related clinical factors.

methodsData of patients who underwent CE for the evaluation of IDA were reviewed from a CE registry in Korea. Additional clinical data were collected by the involved investigators of each hospital through a review of medical records.

resultsAmong a total of 144 patients, the diagnostic yield of CE was 34%. Gastrointestinal (GI) bleeding was found in 6.3% (n=9) of the patients (occult bleeding in four patients and overt bleeding in five patients) during a mean follow-up of 17.8 months. Patients with a positive fecal occult blood test (FOBT) result at the initial diagnosis had a higher rate of GI bleeding after CE (p=0.004). In addition, a positive FOBT result was the only independent predictive factor for GI bleeding (hazard ratio, 5.30; 95% confidence interval, 1.41-19.85; p=0.013).

conclusionPositive FOBT is a predictive factor for GI bleeding during follow-up after CE in patients with unexplained IDA without overt bleeding. Thus, patients with positive FOBT need to be more closely followed up.

Indexed as

Capsule endoscopyFecal occult blood testGastrointestinal bleedingIron deficiency anemiaPredictive factors

Identifiers

PMID33153246
PMCPMC7719424
OpenAlexW3095920642

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.