Evidence map›Paper›PMID 33153205›Full record

ArticleInternational journal of molecular sciences2020

A Rejection Gene Expression Score in Indication and Surveillance Biopsies Is Associated with Graft Outcome.

Betty Chamoun, Anna Caraben, Irina B Torres, Joana Sellares, Raquel Jiménez, Néstor Toapanta, Ignacio Cidraque, Alejandra Gabaldon, Manel Perelló, Ricardo Gonzalo and 3 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Limitations of biopsy-based transcript diagnostics to detect T-cell-mediated allograft rejection.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Betty ChamounNephrology Departments, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain.ORCID 0000-0002-4267-2273
Anna CarabenNephrology Departments, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain.
Irina B TorresNephrology Departments, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain.
Joana SellaresNephrology Departments, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain.
Raquel JiménezNephrology Departments, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain.
Néstor ToapantaNephrology Departments, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain.
Ignacio CidraqueNephrology Departments, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain.
Alejandra GabaldonPathology Departments, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain.
Manel PerellóNephrology Departments, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain.ORCID 0000-0003-1859-5279
Ricardo GonzaloStatistics and Bioinformatics Unit (UEB), Vall d'Hebron Research Institute (VHIR), 08035 Barcelona, Spain.
Francisco O'VallePathology Department, Instituto de Biopatología y Medicina Regenerativa (IBIMER), Instituto de Investigación Biosanitaria (ibs.GRANADA), University of Granada, 18010 Granada, Spain.ORCID 0000-0001-9207-2287
Francesc MoresoNephrology Departments, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain.ORCID 0000-0002-7267-3963
Daniel SerónNephrology Departments, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain.ORCID 0000-0003-2054-653X

Funding

Instituto de Salud Carlos III PI 18/01382Instituto de Salud Carlos III PI 18/01704Instituto de Salud Carlos III REDinREN RD16/0009/0030Sociedad Española de Trasplante-Novartis First grant to Francesc MoresoVall d'Hebron Research Institute Grant to Betty Chamoun
6 · The paper itself

Abstract

Rejection-associated gene expression has been characterized in renal allograft biopsies for cause. The aim is to evaluate rejection gene expression in subclinical rejection and in biopsies with borderline changes or interstitial fibrosis and tubular atrophy (IFTA). We included 96 biopsies. Most differentially expressed genes between normal surveillance biopsies (

Indexed as

Kidney TransplantationTranscriptomeAdultAgedAsymptomatic DiseasesBiopsyFemaleGraft RejectionHumansKidneyKidney DiseasesMaleMicroarray AnalysisMiddle AgedMonitoring, PhysiologicPredictive Value of Testsbiopsiesborderline changesinterstitial fibrosis and tubular atrophymicroarraysrejectionrenal transplantationtranscriptomics

Identifiers

PMID33153205
PMCPMC7672640

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.