Evidence map›Paper›PMID 33153137›Full record

ArticleInternational journal of molecular sciences2020

Kinetic and Equilibrium Studies of Doxorubicin Adsorption onto Carbon Nanotubes.

Dorota Chudoba, Katarzyna Łudzik, Monika Jażdżewska, Sebastian Wołoszczuk

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Dorota ChudobaFaculty of Physics, Adam Mickiewicz University, 61-614 Poznan, Poland.ORCID 0000-0002-2469-3046
Katarzyna ŁudzikFrank Laboratory of Neutron Physics, Joint Institute for Nuclear Research, 141980 Dubna, Russia.ORCID 0000-0003-1749-808X
Monika JażdżewskaFaculty of Physics, Adam Mickiewicz University, 61-614 Poznan, Poland.
Sebastian WołoszczukFaculty of Physics, Adam Mickiewicz University, 61-614 Poznan, Poland.ORCID 0000-0003-0249-0907
Joint Institute for Nuclear Research · RUAdam Mickiewicz University in Poznań · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study provides deep insight into the adsorption process of doxorubicin onto different types of carbon nanotubes that have been proved to show attractive properties as a drug delivery system. The main aim of the work was to propose probable adsorption mechanisms and interactions between the anticancer drug and surface of modified and pristine carbon nanotubes at blood pH. The carbon nanotubes were oxidized to optimize the absorbance efficiency relative to that of pristine multiwalled carbon nanotubes. The adsorption isotherm of the modified system was well described by the Temkin equation. It confirms that the adsorption in the system studied involves also hydrogen and covalent bonding and is exothermic in nature. The experimental kinetic curves of adsorption were fitted to different mathematical models to check if the kinetics of doxorubicin adsorption onto the modified multiwalled carbon nanotubes follows a pseudo-second-order model and the chemical sorption is bound to be the rate-limiting. On the basis of the molecular dynamics simulation, it was shown that

Indexed as

AdsorptionCalorimetry, Differential ScanningComputer SimulationDoxorubicinHydrogen-Ion ConcentrationHydrophobic and Hydrophilic InteractionsKineticsMolecular Dynamics SimulationNanotubes, CarbonSpectrometry, X-Ray EmissionSurface PropertiesThermogravimetryWater Pollutants, ChemicalDoxorubicinNanotubes, CarbonWater Pollutants, Chemicaladsorptioncarbon nanotubesdoxorubicindrug deliverymolecular dynamics simulation

Identifiers

PMID33153137
PMCPMC7663511
OpenAlexW3096305989

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.