Evidence map›Paper›PMID 33153123›Full record

ArticleInternational journal of molecular sciences2020

Emerging Role for Linear and Circular Spermine Oxidase RNAs in Skeletal Muscle Physiopathology.

Jonathan Fernando Reinoso-Sánchez, Giulia Baroli, Guglielmo Duranti, Silvia Scaricamazza, Stefania Sabatini, Cristiana Valle, Mariangela Morlando, Robert Anthony Casero, Irene Bozzoni, Paolo Mariottini and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  4. Article
  5. Review
  6. The Effect ofAntioxidants (Basel, Switzerland) · 2024
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  15. Article
  16. Non-coding RNA basis of muscle atrophy.Molecular therapy. Nucleic acids · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 2 countries.

Jonathan Fernando Reinoso-SánchezDepartment of Science, "Department of Excellence 2018-2022", University of Rome "Roma Tre", 00146 Rome, Italy.
Giulia BaroliDepartment of Science, "Department of Excellence 2018-2022", University of Rome "Roma Tre", 00146 Rome, Italy.
Guglielmo DurantiLaboratory of Biochemistry and Molecular Biology-Department of Movement, Human and Health Sciences, University of Rome "Foro Italico", 00135 Rome, Italy.ORCID 0000-0002-1664-9387
Silvia ScaricamazzaDepartment of Biology, University of Rome "Tor Vergata", 00133 Rome, Italy.
Stefania SabatiniLaboratory of Biochemistry and Molecular Biology-Department of Movement, Human and Health Sciences, University of Rome "Foro Italico", 00135 Rome, Italy.
Cristiana ValleIRCCS Fondazione Santa Lucia, 00179 Rome, Italy.
Mariangela MorlandoDepartment of Pharmaceutical Sciences, "Department of Excellence 2018-2022", University of Perugia, 06123 Perugia, Italy.ORCID 0000-0002-8327-4423
Robert Anthony CaseroSidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA.
Irene BozzoniDepartment of Biology and Biotechnology "Charles Dar win", University of Rome "La Sapienza", 00185 Rome, Italy.
Paolo MariottiniDepartment of Science, "Department of Excellence 2018-2022", University of Rome "Roma Tre", 00146 Rome, Italy.ORCID 0000-0003-1044-7108
Roberta CeciLaboratory of Biochemistry and Molecular Biology-Department of Movement, Human and Health Sciences, University of Rome "Foro Italico", 00135 Rome, Italy.ORCID 0000-0002-8900-8839
Manuela CervelliDepartment of Science, "Department of Excellence 2018-2022", University of Rome "Roma Tre", 00146 Rome, Italy.ORCID 0000-0001-8535-8279
Roma Tre University · ITForo Italico University of Rome · ITIstituto di Farmacologia Traslazionale · ITItalian Institute of Technology · ITJohns Hopkins University · USUniversity of Perugia · ITUniversity of Rome Tor Vergata · IT

Funding

Revealing Epistasis in Alzheimer DiseaseR01AG020135 · NIA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI MARTIN, EDEN R. · 2002 to 2006
$2.7M
Grant to Department of Science, Roma Tre University (MIUR Italy Dipartimento di Eccellenza) ARTICOLO 1, COMMI 314 337 LEGGE 232/2016Research grant from the University of Rome 'Foro Italico' CDR2.BANDO2017SSResearch grant from University of Pennsylvania Orphan Disease Center in partnership with the Snyder-Robinson Foundation MDBR-20-135-SRS (RAC)Research project of basic and technological research approved in the Protocols of Scientific and Technological Bilateral Cooperation funded by the Ministry of Health, Italy-United States of America. 2019 "Whole transcriptome analysis in models of extended MAE0067342
6 · The paper itself

Abstract

Skeletal muscle atrophy is a pathological condition so far without effective treatment and poorly understood at a molecular level. Emerging evidence suggest a key role for circular RNAs (circRNA) during myogenesis and their deregulation has been reported to be associated with muscle diseases. Spermine oxidase (SMOX), a polyamine catabolic enzyme plays a critical role in muscle differentiation and the existence of a circRNA arising from

Indexed as

Amyotrophic Lateral SclerosisAnimalsCell DifferentiationCells, CulturedDisease Models, AnimalFemaleMaleMiceMice, Inbred C57BLMice, TransgenicMuscle Fibers, SkeletalMuscle, SkeletalMuscular AtrophyOxidoreductases Acting on CH-NH Group DonorsPolyamine OxidaseRNA-Binding Protein FUSFUS protein, mouseOxidoreductases Acting on CH-NH Group DonorsPolyamine OxidaseRNA-Binding Protein FUSRNA, CircularRNA, MessengerRNA, UntranslatedSod1 protein, mouseSuperoxide Dismutase-1amyotrophic lateral sclerosis murine modelscircRNAskeletal muscle atrophyspermine oxidase

Identifiers

PMID33153123
PMCPMC7663755
OpenAlexW3095750938

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.