Evidence map›Paper›PMID 33153107›Full record

ArticleInternational journal of molecular sciences2020

Targeted Disruption of Mouse Dip2B Leads to Abnormal Lung Development and Prenatal Lethality.

Rajiv Kumar Sah, Jun Ma, Fatoumata Binta Bah, Zhenkai Xing, Salah Adlat, Zin Ma Oo, Yajun Wang, Noor Bahadar, Ameer Ali Bohio, Farooq Hayel Nagi and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Transcriptomic profiling of mice brain under Bex3 regulation.Turkish journal of biology = Turk biyoloji dergisi · 2022
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Rajiv Kumar SahKey Laboratory of Molecular Epigenetics, Institute of Genetics and Cytology, Northeast Normal University, Changchun 130024, China.
Jun MaWenzhou Institute, University of Chinese Academy of Sciences, Wenzhou 325001, China.
Fatoumata Binta BahKey Laboratory of Molecular Epigenetics, Institute of Genetics and Cytology, Northeast Normal University, Changchun 130024, China.
Zhenkai XingKey Laboratory of Molecular Epigenetics, Institute of Genetics and Cytology, Northeast Normal University, Changchun 130024, China.
Salah AdlatKey Laboratory of Molecular Epigenetics, Institute of Genetics and Cytology, Northeast Normal University, Changchun 130024, China.ORCID 0000-0001-5318-8762
Zin Ma OoKey Laboratory of Molecular Epigenetics, Institute of Genetics and Cytology, Northeast Normal University, Changchun 130024, China.
Yajun WangKey Laboratory of Molecular Epigenetics, Institute of Genetics and Cytology, Northeast Normal University, Changchun 130024, China.
Noor BahadarKey Laboratory of Molecular Epigenetics, Institute of Genetics and Cytology, Northeast Normal University, Changchun 130024, China.
Ameer Ali BohioKey Laboratory of Molecular Epigenetics, Institute of Genetics and Cytology, Northeast Normal University, Changchun 130024, China.
Farooq Hayel NagiKey Laboratory of Molecular Epigenetics, Institute of Genetics and Cytology, Northeast Normal University, Changchun 130024, China.
Xuechao FengKey Laboratory of Molecular Epigenetics, Institute of Genetics and Cytology, Northeast Normal University, Changchun 130024, China.
Luqing ZhangKey Laboratory of Molecular Epigenetics, Institute of Genetics and Cytology, Northeast Normal University, Changchun 130024, China.
Yaowu ZhengKey Laboratory of Molecular Epigenetics, Institute of Genetics and Cytology, Northeast Normal University, Changchun 130024, China.ORCID 0000-0001-8044-1292

Funding

National Natural Science Foundation of China 31301189 and 81270953Natural Science Foundation of Jilin Province 20200201127JC and 20160101344JC
6 · The paper itself

Abstract

Molecular and anatomical functions of mammalian Dip2 family members (Dip2A, Dip2B and Dip2C) during organogenesis are largely unknown. Here, we explored the indispensable role of Dip2B in mouse lung development. Using a LacZ reporter, we explored Dip2B expression during embryogenesis. This study shows that Dip2B expression is widely distributed in various neuronal, myocardial, endothelial, and epithelial cell types during embryogenesis. Target disruption of

Indexed as

Genes, LethalAnimalsEmbryo, MammalianFemaleFetal DeathGene DeletionLungMaleMiceMice, Inbred C57BLMice, KnockoutNerve Tissue ProteinsOrganogenesisPregnancyProtein IsoformsDip2b protein, mousedisco-interacting protein 2, mouseNerve Tissue ProteinsProtein IsoformsDip2bfetal lung developmentgrowth restrictionLacZ expressionmiceprenatal lethalityRNA sequencing

Identifiers

PMID33153107
PMCPMC7663123

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.