Evidence map›Paper›PMID 33153097›Full record

ReviewChildren (Basel, Switzerland)2020

Acute Disseminated Encephalomyelitis: Current Perspectives.

Renata Barbosa Paolilo, Kumaran Deiva, Rinze Neuteboom, Kevin Rostásy, Ming Lim

Open access · goldAbstract readReview
In one paragraph

Review in Children (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 77 citations in OpenAlex.

  1. Pooled it
  2. Article
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  6. Review
  7. Susac syndrome - different treatment approaches for one disease (analysis of case series).Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Review
  8. Article
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  10. Review
  11. Multiple sclerosis: a practical review for pathologists.Journal of pathology and translational medicine · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 5 countries.

Renata Barbosa PaoliloDepartment of Neurology, Hospital das Clínicas, Faculty of Medicine, University of São Paulo (HCFMUSP), São Paulo 05508-060, Brazil.ORCID 0000-0003-3548-8467
Kumaran DeivaDepartment of Pediatric Neurology, Assistance Publique-Hôpitaux de Paris, University Hospitals Paris Saclay, Bicêtre Hospital, 72, Rue G Leclerc, 94270 Le Kremlin Bicêtre, France.
Rinze NeuteboomDepartment of Neurology, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.
Kevin RostásyDepartment of Pediatric Neurology, Vestische Kinder und Jugendklinik, Witten/Herdecke University, 45711 Datteln, Germany.ORCID 0000-0002-2180-5321
Ming LimChildren's Neurosciences, Evelina London Children's Hospital at Guy's and St Thomas' NHS Foundation Trust, London SE1 7EH, UK.
Erasmus MC · NLGuy's and St Thomas' NHS Foundation Trust · GBHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BRInserm · FRWitten/Herdecke University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute disseminated encephalomyelitis (ADEM) is an immune-mediated central nervous system (CNS) disorder, characterized by polyfocal symptoms, encephalopathy and typical magnetic resonance imaging (MRI) findings, that especially affects young children. Advances in understanding CNS neuroimmune disorders as well as the association of myelin oligodendrocyte glycoprotein antibody (MOG-Ab) with both monophasic and recurrent forms of ADEM have led to new insights into its definition, management and outcome. In this review, we aim to provide an update based on current epidemiologic, clinical, radiological and immunopathological aspects and clinical outcome of ADEM.

Indexed as

acquired demyelination syndrome (ADS)acute disseminated encephalomyelitis (ADEM)multiple sclerosis (MS)myelin oligodendrocyte glycoprotein antibody (MOG-Ab)neuromyelitis optica spectrum disorder (NMOSD)optic neuritis (ON)

Identifiers

PMID33153097
PMCPMC7692206
OpenAlexW3096606709

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.