Evidence map›Paper›PMID 33153069›Full record

ReviewMicromachines2020

A Prominent Cell Manipulation Technique in BioMEMS: Dielectrophoresis.

Zeynep Çağlayan, Yağmur Demircan Yalçın, Haluk Külah

Abstract readReview
In one paragraph

Review in Micromachines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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  5. Review
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  8. Review
  9. Article
  10. Separation of Heterotrophic MicroalgaeFrontiers in bioengineering and biotechnology · 2022
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zeynep ÇağlayanDepartment of Electrical and Electronics Engineering, Middle East Technical University, Ankara 06800, Turkey.
Yağmur Demircan YalçınDepartment of Electrical and Electronics Engineering, Middle East Technical University, Ankara 06800, Turkey.ORCID 0000-0002-3363-489X
Haluk KülahDepartment of Electrical and Electronics Engineering, Middle East Technical University, Ankara 06800, Turkey.

Funding

The Republic of Turkey Ministry of Development BAP-2016K121290The Scientific and Technological Research Council of Turkey (TUBITAK) 213E024
6 · The paper itself

Abstract

BioMEMS, the biological and biomedical applications of micro-electro-mechanical systems (MEMS), has attracted considerable attention in recent years and has found widespread applications in disease detection, advanced diagnosis, therapy, drug delivery, implantable devices, and tissue engineering. One of the most essential and leading goals of the BioMEMS and biosensor technologies is to develop point-of-care (POC) testing systems to perform rapid prognostic or diagnostic tests at a patient site with high accuracy. Manipulation of particles in the analyte of interest is a vital task for POC and biosensor platforms. Dielectrophoresis (DEP), the induced movement of particles in a non-uniform electrical field due to polarization effects, is an accurate, fast, low-cost, and marker-free manipulation technique. It has been indicated as a promising method to characterize, isolate, transport, and trap various particles. The aim of this review is to provide fundamental theory and principles of DEP technique, to explain its importance for the BioMEMS and biosensor fields with detailed references to readers, and to identify and exemplify the application areas in biosensors and POC devices. Finally, the challenges faced in DEP-based systems and the future prospects are discussed.

Indexed as

biochipbiomemsbiosensorscancer cellsdiagnosticsdielectrophoresislab-on-a-chipmarker-free particle manipulationmultidrug resistancepoint-of-care

Identifiers

PMID33153069
PMCPMC7693018

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.