Evidence map›Paper›PMID 33153066›Full record

ArticleVaccines2020

Innate and Adaptive Immune Responses against

Catherine B Blackwood, Emel Sen-Kilic, Dylan T Boehm, Jesse M Hall, Melinda E Varney, Ting Y Wong, Shelby D Bradford, Justin R Bevere, William T Witt, F Heath Damron and 1 more

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. International journal of molecular sciences · 2025
    Review
  6. Article
  7. Article
  8. Non-primate animal models for pertussis: back to the drawing board?Applied microbiology and biotechnology · 2022
    Review
  9. Subunit vaccines forFrontiers in immunology · 2022
    Review
  10. Article
  11. Conquering the host:Frontiers in microbiology · 2022
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Catherine B BlackwoodWest Virginia University Vaccine Development Center, Department of Microbiology, Immunology and Cell Biology, 64 Medical Center Drive, Morgantown, WV 26505, USA.
Emel Sen-KilicWest Virginia University Vaccine Development Center, Department of Microbiology, Immunology and Cell Biology, 64 Medical Center Drive, Morgantown, WV 26505, USA.ORCID 0000-0003-1583-2056
Dylan T BoehmWest Virginia University Vaccine Development Center, Department of Microbiology, Immunology and Cell Biology, 64 Medical Center Drive, Morgantown, WV 26505, USA.
Jesse M HallWest Virginia University Vaccine Development Center, Department of Microbiology, Immunology and Cell Biology, 64 Medical Center Drive, Morgantown, WV 26505, USA.
Melinda E VarneyWest Virginia University Vaccine Development Center, Department of Microbiology, Immunology and Cell Biology, 64 Medical Center Drive, Morgantown, WV 26505, USA.
Ting Y WongWest Virginia University Vaccine Development Center, Department of Microbiology, Immunology and Cell Biology, 64 Medical Center Drive, Morgantown, WV 26505, USA.
Shelby D BradfordWest Virginia University Vaccine Development Center, Department of Microbiology, Immunology and Cell Biology, 64 Medical Center Drive, Morgantown, WV 26505, USA.
Justin R BevereWest Virginia University Vaccine Development Center, Department of Microbiology, Immunology and Cell Biology, 64 Medical Center Drive, Morgantown, WV 26505, USA.
William T WittWest Virginia University Vaccine Development Center, Department of Microbiology, Immunology and Cell Biology, 64 Medical Center Drive, Morgantown, WV 26505, USA.
F Heath DamronWest Virginia University Vaccine Development Center, Department of Microbiology, Immunology and Cell Biology, 64 Medical Center Drive, Morgantown, WV 26505, USA.
Mariette BarbierWest Virginia University Vaccine Development Center, Department of Microbiology, Immunology and Cell Biology, 64 Medical Center Drive, Morgantown, WV 26505, USA.ORCID 0000-0002-3250-3636
West Virginia University · US

Funding

WV INBRE: The Inhibitor of Growth Family Member 4 (ING4) inhibits L-Type Amino Acid Transporter 1 (LAT1) expression to suppress Breast CancerP20GM103434 · NIGMS · MARSHALL UNIVERSITY · PI Travis Salisbury · 2012 to 2026
$61.1M
WVU Flow Cytometry and Single Cell Core Facility (FCSCCF)P20GM121322 · NIGMS · WEST VIRGINIA UNIVERSITY · PI Dominique Bollino · 2018 to 2026
$22.4M
West Virginia Flow Cytometry Core FacilityP30GM103488 · NIGMS · WEST VIRGINIA UNIVERSITY · PI GIBSON, LAURA F. · 2012 to 2016
$4.8M
Vaccine Development Against Bacterial Pathogens Based on iron Acquisition ProteinsR01AI141671 · NIAID · WEST VIRGINIA UNIVERSITY · PI BARBIER, MARIETTE · 2019 to 2023
$2.5M
Special Becton Dickinson Fortessa Flow CytometerS10OD016165 · OD · WEST VIRGINIA UNIVERSITY · PI CUFF, CHRISTOPHER F · 2013 to 2013
$384k
LIPID METABOLISM OF KERATINOCYTESK08AR001610 · NIAMS · UNIVERSITY OF IOWA · PI MADISON, KATHI C · 1986 to 1990
–
Cystic Fibrosis Foundation BARBIE1610Cystic Fibrosis Foundation BARBIE18GODivision of Science and Research, WV Higher Education Policy Commission HEPC.dsr.18.6NIAID NIH HHS R01 AI141671NIGMS NIH HHS P20 GM103434NIGMS NIH HHS P20 GM121322NIGMS NIH HHS P30 GM103488NIH HHS S10 OD016165West Virginia Space Grant Consortium Graduate Research FellowshipWest Virginia University Vaccine Development Center Graduate Student Pilot Project GrantsWVU Immunology, Microbiology and Cell Biology Department Dr. Jennifer Gosling Scholarship
6 · The paper itself

Abstract

Whole cell vaccines are frequently the first generation of vaccines tested for pathogens and can inform the design of subsequent acellular or subunit vaccines. For respiratory pathogens, administration of vaccines at the mucosal surface can facilitate the generation of a localized mucosal immune response. Here, we examined the innate and vaccine-induced immune responses to infection by two respiratory pathogens:

Indexed as

Bordetella pertussisintranasalmucosalpneumoniaPseudomonas aeruginosavaccinationvaccine developmentwhole cell vaccinewhooping cough

Identifiers

PMID33153066
PMCPMC7712645
OpenAlexW3097189910

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.