Evidence map›Paper›PMID 33152672›Full record

ArticleDrug and alcohol dependence2020

Health economic design for cost, cost-effectiveness and simulation analyses in the HEALing Communities Study.

Arnie P Aldridge, Carolina Barbosa, Joshua A Barocas, Joshua L Bush, Jagpreet Chhatwal, Kristin J Harlow, Ayaz Hyder, Benjamin P Linas, Kathryn E McCollister, Jake R Morgan and 7 more

Open access · hybridAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Trial
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  8. Informing evidence-based medicine for opioid use disorder using pharmacoeconomic studies.Expert review of pharmacoeconomics & outcomes research · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. The HEALing (Helping to End Addiction Long-termDrug and alcohol dependence · 2020
    Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 8 institutions in 1 country.

Arnie P AldridgeRTI International, 3040 East Cornwallis Road, RTP, NC, 27709, United States. Electronic address: aaldridge@rti.org.
Carolina BarbosaRTI International, 3040 East Cornwallis Road, RTP, NC, 27709, United States.
Joshua A BarocasBoston Medical Center, One Boston Medical Center Pl, Boston, MA, 02118, United States; University of Pennsylvania School of Nursing, 418 Curie Blvd, Philadelphia, PA, 19104, United States.
Joshua L BushUniversity of Kentucky, College of Public Health, 111 Washington Ave., Lexington, KY, 40536, United States.
Jagpreet ChhatwalMassachusetts General Hospital, Harvard Medical School, 55 Fruit St, Boston, MA, 02114, United States.
Kristin J HarlowThe Ohio State University College of Public Health, 250 Cunz Hall, 1841 Neil Ave., Columbus, OH, 43210, United States.
Ayaz HyderThe Ohio State University College of Public Health, 250 Cunz Hall, 1841 Neil Ave., Columbus, OH, 43210, United States.
Benjamin P LinasBoston Medical Center, One Boston Medical Center Pl, Boston, MA, 02118, United States.
Kathryn E McCollisterUniversity of Miami Miller School of Medicine, 1120 NW 14(th)Street, Suite 1019, Miami, FL, 33136, United States.
Jake R MorganBoston University School of Public Health, 715 Albany St, Boston, MA, 02118, United States.
Sean M MurphyWeill Cornell Medicine, 425 East 61(st)Street, Suite 301, New York, NY, 10065, United States.
Caroline SavitzkyBoston Medical Center, One Boston Medical Center Pl, Boston, MA, 02118, United States.
Bruce R SchackmanWeill Cornell Medicine, 425 East 61(st)Street, Suite 301, New York, NY, 10065, United States.
Eric E SeiberThe Ohio State University College of Public Health, 250 Cunz Hall, 1841 Neil Ave., Columbus, OH, 43210, United States.
Laura E StarbirdColumbia University, New York, NY, 10027, United States; University of Pennsylvania School of Nursing, 418 Curie Blvd, Philadelphia, PA, 19104, United States.
Jennifer VillaniNational Institute on Drug Abuse, 3WFN RM08A45, MSC 6025, 301 North Stonestreet Ave, Rockville, MD, 20852, United States.
Gary A ZarkinRTI International, 3040 East Cornwallis Road, RTP, NC, 27709, United States.
RTI International · USThe Ohio State University · USBoston Medical Center · USUniversity of Pennsylvania · USBoston University · USHarvard University · USNational Institute on Drug Abuse · USUniversity of Kentucky · US

Funding

MassHEAL - Reducing overdose deaths by 40% (2019-2023)UM1DA049412 · NIDA · BOSTON MEDICAL CENTER · PI SAMET, JEFFREY H. · 2019 to 2023
$82.9M
Kentucky CAN HEAL (Communities and Networks Helping End Addiction Long-term)UM1DA049406 · NIDA · UNIVERSITY OF KENTUCKY · PI WALSH, SHARON L. · 2019 to 2022
$81.7M
CHASE: An Innovative County-Level Public Health Response to the Opioid Epidemic in New York StateUM1DA049415 · NIDA · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI EL-BASSEL, NABILA, GILBERT, LOUISA · 2019 to 2023
$77.3M
Optimizing HEALing in Ohio Communities (OHiO)-Health Equity SupplementUM1DA049417 · NIDA · OHIO STATE UNIVERSITY · PI FREISTHLER, BRIDGET J, WINHUSEN, T JOHN · 2019 to 2023
$66.3M
Translational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI CURT G BECKWITH · 1998 to 2026
$51.7M
HEALing Communities Study Health Equity ResearchUM1DA049394 · NIDA · RESEARCH TRIANGLE INSTITUTE · PI GLASGOW, LASHAWN, OGA, EMMANUEL AJA · 2019 to 2023
$40.6M
Utilization of health services after engagement with opioid use disorder (OUD) treatment provider by individuals with and without post-traumatic stress disorderP30DA040500 · NIDA · WEILL MEDICAL COLL OF CORNELL UNIV · PI ZACHARY Franklin MEISEL · 2015 to 2026
$20.7M
XENOBIOTIC TRANSFER INTO MILK NITROFURANTOINM01RR002602 · NCRR · UNIVERSITY OF KENTUCKY · PI REID, MICHAEL B · 1985 to 2007
$12.1M
Implementation of PrEP for Women Who Inject Drugs through Practice Facilitation in Primary and Reproductive Health CareK01DA051348 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI STARBIRD, LAURA · 2020 to 2024
$962k
NCRR NIH HHS M01 RR002602NIAID NIH HHS P30 AI042853NIDA NIH HHS K01 DA051348NIDA NIH HHS P30 DA040500NIDA NIH HHS UM1 DA049394NIDA NIH HHS UM1 DA049406NIDA NIH HHS UM1 DA049412NIDA NIH HHS UM1 DA049415NIDA NIH HHS UM1 DA049417NINR NIH HHS L30 NR018771
6 · The paper itself

Abstract

backgroundThe HEALing Communities Study (HCS) is designed to implement and evaluate the Communities That HEAL (CTH) intervention, a conceptually driven framework to assist communities in selecting and adopting evidence-based practices to reduce opioid overdose deaths. The goal of the HCS is to produce generalizable information for policy makers and community stakeholders seeking to implement CTH or a similar community intervention. To support this objective, one aim of the HCS is a health economics study (HES), the results of which will inform decisions around fiscal feasibility and sustainability relevant to other community settings.

methodsThe HES is integrated into the HCS design: an unblinded, multisite, parallel arm, cluster randomized, wait list-controlled trial of the CTH intervention implemented in 67 communities in four U.S. states: Kentucky, Massachusetts, New York, and Ohio. The objectives of the HES are to estimate the economic costs to communities of implementing and sustaining CTH; estimate broader societal costs associated with CTH; estimate the cost-effectiveness of CTH for overdose deaths avoided; and use simulation modeling to evaluate the short- and long-term health and economic impact of CTH, including future overdose deaths avoided and quality-adjusted life years saved, and to develop a simulation policy tool for communities that seek to implement CTH or a similar community intervention. DISCUSSION: The HCS offers an unprecedented opportunity to conduct health economics research on solutions to the opioid crisis and to increase understanding of the impact and value of complex, community-level interventions.

Indexed as

Cost-Benefit AnalysisDrug OverdoseEvidence-Based PracticeHumansMassachusettsNew YorkOhioOpiate OverdoseQuality-Adjusted Life YearsRandomized Controlled Trials as TopicCost-effectivenessEconomic evaluationHEALing Communities StudyHelping to end addiction long termOpioid use disorderOverdoseSimulation

Identifiers

PMID33152672
PMCPMC7532345
OpenAlexW3091003335

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.