Evidence map›Paper›PMID 33152642›Full record

ArticlePlacenta2021

Trophoblast inclusions in the human placenta: Identification, characterization, quantification, and interrelations of subtypes.

Harvey J Kliman, Morgan R Firestein, Katherine M Hofmann, Kristin M Milano, Parker H Holzer, Lucy T Brink, Hein J Odendaal, William P Fifer

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Placenta, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Placental Alterations in Autism Spectrum Disorder: An In Silico Approach to circRNA-miRNA-mRNA Networks.International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience · 2025
    Article
  2. Article
  3. Placental Pathology Findings in Unexplained Pregnancy Losses.Reproductive sciences (Thousand Oaks, Calif.) · 2024
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Harvey J KlimanDepartment of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, CT, USA. Electronic address: harvey.kliman@yale.edu.
Morgan R FiresteinDepartment of Psychiatry, Columbia University Irving Medical Center, New York, NY, USA.
Katherine M HofmannYale College, Yale University, New Haven, CT, USA.
Kristin M MilanoDepartment of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, CT, USA.
Parker H HolzerDepartment of Statistics & Data Science, Yale University, New Haven, CT, USA.
Lucy T BrinkDepartment of Obstetrics and Gynaecology, Faculty of Medicine and Health Science, Stellenbosch University, Cape Town, Western Cape, South Africa.
Hein J OdendaalDepartment of Obstetrics and Gynaecology, Faculty of Medicine and Health Science, Stellenbosch University, Cape Town, Western Cape, South Africa.
William P FiferDepartment of Psychiatry, Columbia University Irving Medical Center, New York, NY, USA; Department of Obstetrics and Gynaecology, Faculty of Medicine and Health Science, Stellenbosch University, Cape Town, Western Cape, South Africa; Division of Developmental Neuroscience, New York State Psychiatric Institute, New York, NY, USA; Department of Pediatrics, Columbia University Irving Medical Center, New York, NY, USA.

Funding

Prenatal Alcohol in Sudden Infant Death Syndrome and Stillbirth (PASS) NetworkU01HD045935 · NICHD · UNIVERSITY OF SOUTH DAKOTA · PI ELLIOTT, AMY J · 2003 to 2015
$16.9M
Prenatal Alcohol in Sudden Infant Death Syndrome and Stillbirth (PASS) NetworkU01AA016501 · NIAAA · STELLENBOSCH UNIVERSITY · PI ODENDAAL, HENDRIK JOHANNES · 2006 to 2015
$10.0M
Safe PASSage Study Administrative Supplement - Effects of Overnight Maternal SleeU01HD055154 · NICHD · DM-STAT, INC. · PI DUKES, KIMBERLY A. · 2006 to 2017
$9.7M
Prenatal Alcohol Sudden Infant Death Syndrome/StillbirthU01HD045991 · NICHD · CHILDREN'S HOSPITAL BOSTON · PI KINNEY, HANNAH CHASE · 2003 to 2015
$8.4M
Prenatal Alcohol in Sudden Infant Death Syndrome and Stillbirth (PASS) NetworkU01HD055155 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI FIFER, WILLIAM P., MYERS, MICHAEL MORGAN · 2006 to 2015
$7.1M
NIAAA NIH HHS U01 AA016501NICHD NIH HHS U01 HD045935NICHD NIH HHS U01 HD045991NICHD NIH HHS U01 HD055154NICHD NIH HHS U01 HD055155
6 · The paper itself

Abstract

We sought to examine placentas enriched for trophoblast inclusions (TIs) in order to characterize, quantify, and examine the interrelations between subtypes of TIs to better understand their underlying biology. We examined a cohort of 600 placentas from deliveries between 20

Indexed as

AdultBiomarkersCalcinosisFemaleGestational AgeHumansImage Processing, Computer-AssistedInclusion BodiesPlacentaPregnancyPregnancy OutcomeTrophoblastsYoung AdultBiomarkersFoldingGenetic markersPathologyPlacentaTrophoblast inclusions

Identifiers

PMID33152642
PMCPMC8448462

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.