Evidence map›Paper›PMID 33152529›Full record

ArticleProstaglandins & other lipid mediators2021

Lipoxin A4 promotes reduction and antibiotic efficacy against Pseudomonas aeruginosa biofilm.

J M Thornton, J M Walker, P Y Kadiyam Sundarasivarao, B W Spur, A Rodriguez, K Yin

Open access · greenAbstract read
In one paragraph

Article in Prostaglandins & other lipid mediators, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

  1. AA in Rheumatoid Arthritis and Lupus.Reviews of physiology, biochemistry and pharmacology · 2027
    Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Lipoxin AFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2023
    Article
  9. Article
  10. Review
  11. Review
  12. Different Concentrations ofFrontiers in cellular and infection microbiology · 2021
    Article
  13. Quorum Sensing Inhibiting Activity of Cefoperazone and Its Metallic Derivatives onFrontiers in cellular and infection microbiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

J M ThorntonDepartment of Cell Biology and Neuroscience, Rowan University School of Osteopathic Medicine, Stratford, NJ, USA.
J M WalkerDepartment of Cell Biology and Neuroscience, Rowan University School of Osteopathic Medicine, Stratford, NJ, USA.
P Y Kadiyam SundarasivaraoDepartment of Cell Biology and Neuroscience, Rowan University School of Osteopathic Medicine, Stratford, NJ, USA.
B W SpurDepartment of Cell Biology and Neuroscience, Rowan University School of Osteopathic Medicine, Stratford, NJ, USA.
A RodriguezDepartment of Cell Biology and Neuroscience, Rowan University School of Osteopathic Medicine, Stratford, NJ, USA.
K YinDepartment of Cell Biology and Neuroscience, Rowan University School of Osteopathic Medicine, Stratford, NJ, USA. Electronic address: yinki@rowan.edu.
Rowan University · US

Funding

Antimicrobial mechanisms of Specialized Proresolving MedicatorsR01AI128202 · NIAID · ROWAN UNIVERSITY SCHOOL/OSTEOPATHIC MED · PI YIN, KINGSLEY E · 2018 to 2022
$2.0M
NIAID NIH HHS R01 AI128202
6 · The paper itself

Abstract

Pseudomonas aeruginosa (P. aeruginosa) is an opportunistic bacterium commonly found in wound infections and airways of cystic fibrosis patients. P. aeruginosa readily forms biofilms which can reduce the efficacy of antibiotics used to eradicate the pathogen. We have previously shown that a Specialized Pro-resolving Mediator (SPM), Lipoxin A4 (LxA

Indexed as

Anti-Bacterial AgentsBiofilmsCiprofloxacinLipoxinsPseudomonas aeruginosaGene Expression Regulation, BacterialHumansMicrobial Sensitivity TestsAnti-Bacterial AgentsCiprofloxacinlipoxin A4LipoxinsAntibioticsbiofilmLipoxin A4Pseudomonas aeruginosaResolvin D2

Identifiers

PMID33152529
PMCPMC7856039
OpenAlexW3097161563

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.