Evidence map›Paper›PMID 33152484›Full record

ArticleJoint bone spine2021

COVID-19 in French patients with chronic inflammatory rheumatic diseases: Clinical features, risk factors and treatment adherence.

Félicie Costantino, Léa Bahier, Luis Coronel Tarancón, Ariane Leboime, François Vidal, Lamouri Bessalah, Maxime Breban, Maria-Antonietta D'Agostino

Abstract read
In one paragraph

Article in Joint bone spine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Impact of COVID-19 Pandemic on Adherence to Chronic Therapies: A Systematic Review.International journal of environmental research and public health · 2023
    Pooled it
  3. Pooled it
  4. Guideline
  5. Observational
  6. Article
  7. Article
  8. Article
  9. The Impact of the COVID-19 Pandemic on Inflammatory Rheumatic Diseases.Journal of clinical practice and research · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Revue du rhumatisme (Ed. francaise : 1993) · 2022
    Article
  14. Article
  15. Review
  16. Article
  17. Pain and Affected Symptoms of Patients with Rheumatoid Arthritis During COVID-19 Period.Pain management nursing : official journal of the American Society of Pain Management Nurses · 2022
    Article
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  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Félicie CostantinoInserm U1173, Infection et inflammation, Laboratory of Excellence INFLAMEX, Université Paris-Saclay, UVSQ, Montigny-Le-Bretonneux, France; Rheumatology Department, AP-HP, Ambroise Paré Hospital, 9, avenue Charles-de-Gaulle, 92100 Boulogne-Billancourt, France.
Léa BahierRheumatology Department, AP-HP, Ambroise Paré Hospital, 9, avenue Charles-de-Gaulle, 92100 Boulogne-Billancourt, France.
Luis Coronel TarancónRheumatology Department, AP-HP, Ambroise Paré Hospital, 9, avenue Charles-de-Gaulle, 92100 Boulogne-Billancourt, France.
Ariane LeboimeRheumatology Department, AP-HP, Ambroise Paré Hospital, 9, avenue Charles-de-Gaulle, 92100 Boulogne-Billancourt, France.
François VidalRheumatology Department, AP-HP, Ambroise Paré Hospital, 9, avenue Charles-de-Gaulle, 92100 Boulogne-Billancourt, France.
Lamouri BessalahBEPATIENT, Paris, France.
Maxime BrebanInserm U1173, Infection et inflammation, Laboratory of Excellence INFLAMEX, Université Paris-Saclay, UVSQ, Montigny-Le-Bretonneux, France; Rheumatology Department, AP-HP, Ambroise Paré Hospital, 9, avenue Charles-de-Gaulle, 92100 Boulogne-Billancourt, France.
Maria-Antonietta D'AgostinoInserm U1173, Infection et inflammation, Laboratory of Excellence INFLAMEX, Université Paris-Saclay, UVSQ, Montigny-Le-Bretonneux, France; Rheumatology Department, AP-HP, Ambroise Paré Hospital, 9, avenue Charles-de-Gaulle, 92100 Boulogne-Billancourt, France. Electronic address: felicie.costantino@inserm.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore how patients with chronic inflammatory rheumatic diseases (CIRDs) coped with their disease during the COVID-19 pandemic and to identify possible predictive factors of SARS-CoV-2 infection in this population.

methodsPatients followed in a single rheumatology department in France or registered on the Spondy+ platform, a secure e-health platform for spondyloarthritis patients, were invited to complete a questionnaire focused on their experiences around COVID19 symptoms, testing and medications access during the lockdown period. Descriptive statistics were used to report questionnaire's results. Factors associated with COVID-19 or with treatment discontinuation were assessed by logistic regression.

resultsWe obtained 655 answers from the 2,081 contacted patients: 474 with spondyloarthritis, 129 with rheumatoid arthritis and 52 with psoriatic arthritis. The population was predominantly female (61.8%) with a mean age of 51.0±13.4 years. Incidence of COVID-19 was 6.9% (95%CI: 5.1-9.2%), including 12 confirmed and 33 highly suspicious cases. No death was observed and five patients needed to be hospitalized. Factors independently associated with an increased risk of infection were SARS-CoV-2 exposure, younger age and non-smoking. More than 30% of the patients suspended or decreased the dosage of one of their drugs during the lockdown period. This was followed in 63.4% of them by increased disease activity. Modifications were mostly motivated by fear of contagion (79.3%).

conclusionWe did not observe any increase of incidence or severity of COVID-19 in patients suffering of the 3 most common CIRDs. This survey also adds evidence of the safety of anti-rheumatic drugs use regarding COVID-19.

Indexed as

PandemicsSARS-CoV-2Treatment Adherence and ComplianceAntirheumatic AgentsComorbidityCOVID-19FemaleFranceGlucocorticoidsHumansMaleMiddle AgedPrognosisRetrospective StudiesRheumatic DiseasesRisk FactorsAntirheumatic AgentsGlucocorticoidsCOVID-19Non-steroidal anti-inflammatory drugsPsoriatic arthritisRheumatoid arthritisSpondyloarthritis

Identifiers

PMID33152484
PMCPMC7605756

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.