Evidence map›Paper›PMID 33152356›Full record

ArticleGastroenterology2021

CRIg

Zhenlong Luo, Yudong Ji, Hong Gao, Felipe Castellani Gomes Dos Reis, Gautam Bandyopadhyay, Zhongmou Jin, Crystal Ly, Ya-Ju Chang, Dinghong Zhang, Deepak Kumar and 1 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers.

0numbers the graph read from it
0cells of the map it votes in
84citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

84 citing papers in PubMed, 107 citations in OpenAlex.

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24 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Zhenlong LuoDivision of Endocrinology and Metabolism, Department of Medicine, University of California, San Diego, California; Department of Gastroenterology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Yudong JiDivision of Endocrinology and Metabolism, Department of Medicine, University of California, San Diego, California; Department of Anesthesiology, Institute of Anesthesiology and Critical Care, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Hong GaoDivision of Endocrinology and Metabolism, Department of Medicine, University of California, San Diego, California.
Felipe Castellani Gomes Dos ReisDivision of Endocrinology and Metabolism, Department of Medicine, University of California, San Diego, California.
Gautam BandyopadhyayDivision of Endocrinology and Metabolism, Department of Medicine, University of California, San Diego, California.
Zhongmou JinDivision of Biological Sciences, University of California, San Diego, California.
Crystal LyDivision of Biological Sciences, University of California, San Diego, California.
Ya-Ju ChangDivision of Endocrinology and Metabolism, Department of Medicine, University of California, San Diego, California.
Dinghong ZhangDivision of Endocrinology and Metabolism, Department of Medicine, University of California, San Diego, California.
Deepak KumarDivision of Endocrinology and Metabolism, Department of Medicine, University of California, San Diego, California.
Wei YingDivision of Endocrinology and Metabolism, Department of Medicine, University of California, San Diego, California. Electronic address: weying@health.ucsd.edu.
University of California San Diego · USTongji University · CNUnion Hospital · CN

Funding

Transgenic & Knock-out MouseP30DK063491 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PETER J TONTONOZ · 2003 to 2026
$40.4M
U of Calif, San Diego Neuroscience Microscopy ImagingP30NS047101 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GLEESON, JOSEPH G, ZHENG, BINHAI · 2003 to 2022
$9.0M
Adipose tissue macrophages secrete exosome-miRs as paracrine/endocrine molecules to directly modulate insulin target cell function in response to obesityR00DK115998 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI YING, WEI · 2020 to 2022
$739k
NIDDK NIH HHS P30 DK063491NIDDK NIH HHS R00 DK115998NINDS NIH HHS P30 NS047101
6 · The paper itself

Abstract

BACKGROUND &

aimsLiver CRIg

methodsWe performed studies with CRIg

resultsGut mEVs can reach metabolic tissues in obesity. Liver CRIg

conclusionsDeficiency of CRIg

Indexed as

AnimalsComplement C3Cyclic Guanosine Monophosphate-Adenosine Monophosphate SynthaseDiet, High-FatDisease Models, AnimalDNA, BacterialExtracellular VesiclesGastrointestinal MicrobiomeHepatitisHumansInsulin ResistanceIntestinal MucosaKupffer CellsLiverMembrane ProteinsMicecGAS protein, mouseComplement C3Cyclic Guanosine Monophosphate-Adenosine Monophosphate SynthaseDNA, BacterialMembrane ProteinsNucleotidyltransferasesReceptors, ComplementSting1 protein, mouseSTING ProteinVSIG4 protein, mouseExtracellular VesicleMicrobial DNAObesityTissue Inflammation

Identifiers

PMID33152356
PMCPMC7878308
OpenAlexW3097454915

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.