ArticleHormones and behavior2021
The role of dopamine signaling in prairie vole peer relationships.
Article in Hormones and behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 37 citations in OpenAlex.
- Adolescent social instability stress alters social processes in male prairie voles.Frontiers in behavioral neuroscience · 2026Article
- Impact of Cesarean Delivery on Reward Behavior and Tyrosine Hydroxylase in the Nucleus Accumbens of Adult Prairie Vole Offspring.Developmental psychobiology · 2026Article
- Comparative gene editing reduces dopamine receptor levels across rodent species.bioRxiv : the preprint server for biology · 2025Article
- Distinct subcircuits within the mesolimbic dopamine system encode the salience and valence of social stimuli.Psychopharmacology · 2025Article
- Oxytocin receptors mediate social selectivity in prairie vole peer relationships.Current biology : CB · 2025Article
- Behavioral sex differences in the developmental emergence and selectivity of partner preferences in prairie voles.Hormones and behavior · 2025Article
- The effects of social loss and isolation on partner odor investigation and dopamine and oxytocin receptor expression in female prairie voles.Neuropharmacology · 2025Article
- A review of the effects of different types of social behaviors on the recruitment of neuropeptides and neurotransmitters in the nucleus accumbens.Frontiers in neuroendocrinology · 2025Review
- Sex-Specific Impacts of Early Life Sleep Disruption: Ethanol Seeking, Social Interaction, and Anxiety Are Differentially Altered in Adolescent Prairie Voles.Developmental psychobiology · 2024Article
- Familiarity and social relationships in degus (Ethology : formerly Zeitschrift fur Tierpsychologie · 2024Article
- Maladaptive cardiac and behavioral reactivity to repeated vicarious stress exposure in socially bonded male prairie vole siblings.Autonomic neuroscience : basic & clinical · 2024Article
- Corticotropin-releasing factor and GABA in the ventral tegmental area modulate partner preference formation in male and female prairie voles (Frontiers in neuroscience · 2024Article
- Peer Social Environment Impacts Behavior and Dopamine D1 Receptor Density in Prairie Voles (Microtus ochrogaster).Neuroscience · 2023Article
- Article
- Sex differences in the reward value of familiar mates in prairie voles.Genes, brain, and behavior · 2022Article
- Selectivity and Sociality: Aggression and Affiliation Shape Vole Social Relationships.Frontiers in behavioral neuroscience · 2022Review
- Hearing, touching, and multisensory integration during mate choice.Frontiers in neural circuits · 2022Review
- Article
- Differential paraventricular nucleus activation and behavioral responses to social isolation in prairie voles following environmental enrichment with and without physical exercise.Social neuroscience · 2021Article
- Sex-specific Disruption of the Prairie Vole Hypothalamus by Developmental Exposure to a Flame Retardant Mixture.Endocrinology · 2021Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Dopamine signaling mediates the formation of some types of social relationships, including reproductive pair bonds in the socially monogamous prairie vole (Microtus ochrogaster). In addition to these pair bonds with mates, prairie voles demonstrate selective preferences for familiar same-sex peers. The dependence of peer relationships on dopamine signaling has not been tested, and the mechanisms supporting these relationships may differ from those underlying pair bonds. We examined the effects of pharmacological manipulations of dopamine signaling on peer partner preference and socially conditioned place preference in female prairie voles. Haloperidol blockade of dopamine receptors at multiple doses did not alter selective preferences for familiar same-sex partners, suggesting that dopamine neurotransmission is not necessary for the formation of prairie vole peer relationships, unlike mate relationships. Dopamine receptor agonist apomorphine facilitated peer partner preferences under conditions normally insufficient for partner preference formation; however, in the absence of effects from blockade, it is difficult to distinguish between a role for dopamine in partner preference formation and the generally rewarding properties of a dopamine agonist. Prairie voles exhibited socially conditioned place preferences for new but not long-term same-sex peers, and these preferences were not blocked by haloperidol. These results suggest that prairie vole peer relationships are less dependent on dopamine signaling than pair bonds, while still being rewarding. The data support distinct roles of dopamine and motivation in prairie vole peer relationships relative to mate relationships, suggesting that reproductive bonds are mediated differently from non-reproductive ones.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.