Evidence map›Paper›PMID 33152145›Full record

ArticleAngewandte Chemie (International ed. in English)2021

Fabrication of Aptamer-Modified Paper Electrochemical Devices for On-Site Biosensing.

Haixiang Yu, Zhimin Chen, Yingzhu Liu, Obtin Alkhamis, Zhiping Song, Yi Xiao

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Wearable biosensors for human fatigue diagnosis: A review.Bioengineering & translational medicine · 2023
    Review
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  3. Article
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  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Haixiang YuDepartment of Chemistry and Biochemistry, Florida International University, 11200 SW 8th St, Miami, FL, 33199, USA.
Zhimin ChenDepartment of Chemistry and Biochemistry, Florida International University, 11200 SW 8th St, Miami, FL, 33199, USA.
Yingzhu LiuDepartment of Chemistry and Biochemistry, Florida International University, 11200 SW 8th St, Miami, FL, 33199, USA.
Obtin AlkhamisDepartment of Chemistry and Biochemistry, Florida International University, 11200 SW 8th St, Miami, FL, 33199, USA.
Zhiping SongDepartment of Chemistry and Biochemistry, Florida International University, 11200 SW 8th St, Miami, FL, 33199, USA.
Yi XiaoDepartment of Chemistry and Biochemistry, Florida International University, 11200 SW 8th St, Miami, FL, 33199, USA.ORCID 0000-0001-7278-9811

Funding

Homogeneous Nuclease-Assisted SELEX for Rapid Isolation of Cross-Reactive, Functionalized Aptamers for Synthetic CannabinoidsR21DA045334 · NIDA · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI XIAO, YI · 2019 to 2020
$334k
NIDA NIH HHS R21 DA045334
6 · The paper itself

Abstract

Electrochemical aptamer-based (E-AB) sensors offer a powerful and general means for analyte detection in complex samples for various applications. Paper-based E-AB sensors could enable portable, low-cost, and rapid detection of a broad range of targets, but it has proven challenging to fabricate suitable three-electrode systems on paper. Here, we demonstrate a simple, economic, and environmentally friendly strategy for fabricating aptamer-modified paper electrochemical devices (PEDs) via ambient vacuum filtration. The material, shape, size, and thickness of the three-electrode PED system can be fully customized. We developed aptamer-modified PEDs that enable sensitive and specific detection of small molecules in minimally processed biosamples. The sensitivity and stability of the PEDs are comparable to E-AB sensors based on commercial gold electrodes. We believe our strategy can lead to the development of high performance PEDs for the on-site detection of a variety of analytes.

Indexed as

PaperAptamers, NucleotideBiosensing TechniquesElectrochemical TechniquesElectrodesGoldMetal NanoparticlesAptamers, NucleotideGoldaptamersbiosensorsnanomaterialspaper electrochemical devicessmall molecules

Identifiers

PMID33152145
PMCPMC7902431

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.