ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2022
Clinical and gated SPECT MPI parameters associated with super-response to cardiac resynchronization therapy.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 20 citations in OpenAlex.
- A Prospective Pilot Study for Prognosis of Cardiac Resynchronization Therapy Super-Response Using Electrical and Mechanical Dyssynchrony Assessment in Patients with Heart Failure and Strauss Left Bundle Branch Block Criteria.Life (Basel, Switzerland) · 2025Article
- A predictive model of super response to cardiac resynchronization therapy in short-term period.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2024Article
- A machine learning method integrating ECG and gated SPECT for cardiac resynchronization therapy decision support.European journal of nuclear medicine and molecular imaging · 2023Article
- Prognostic Role of Diastolic Left Ventricular Mechanical Dyssynchrony by Gated Single Photon Emission Computed Tomography Myocardial Perfusion Imaging in Post-Myocardial Infarction.World journal of nuclear medicine · 2023Article
- Left ventricular mechanical dyssnchrony: A potential new marker for 3-vessel CAD.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Review of cardiovascular imaging in the Journal of Nuclear Cardiology 2022: single photon emission computed tomography.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Review
- Super-Responders in Moderate-Severe Psoriasis under Guselkumab Treatment: Myths, Realities and Future Perspectives.Life (Basel, Switzerland) · 2022Article
- Atopic Dermatitis: Background, Objectives and Future Perspectives (Superresponders).Life (Basel, Switzerland) · 2022Article
- Moving forward with motion reduction, detection and correction in cardiac PET.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Mechanical dyssynchrony and super-response to CRT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
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Authors and funding
16 authors at 12 institutions in 10 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe sought to evaluate the behavior of cardiac mechanical synchrony as measured by phase SD (PSD) derived from gated MPI SPECT (gSPECT) in patients with super-response after CRT and to evaluate the clinical and imaging characteristics associated with super-response.
methods158 subjects were evaluated with gSPECT before and 6 months after CRT. Patients with an improvement of LVEF > 15% and NYHA class I/II or reduction in LV end-systolic volume > 30% and NYHA class I/II were labeled as super-responders (SR).
results34 patients were classified as super-responders (22%) and had lower PSD (32° ± 17°) at 6 months after CRT compared to responders (45° ± 24°) and non-responders 46° ± 28° (P = .02 for both comparisons). Regression analysis identified predictors independently associated with super-response to CRT: absence of previous history of CAD (odds ratio 18.7; P = .002), absence of diabetes mellitus (odds ratio 13; P = .03), and history of hypertension (odds ratio .2; P = .01).
conclusionLV dyssynchrony after CRT implantation, but not at baseline, was significantly better among super-responders compared to non-super-responders. The absence of diabetes, absence of CAD, and history of hypertension were independently associated with super-response after CRT.
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