ArticlePloS one2020
Ion release and recharge from a fissure sealant containing amorphous calcium phosphate.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 15 citations in OpenAlex.
- Comparison of novel bioactive nanosilver-reinforced sealant with three bioactive materials as pit and fissure sealants: an in vitro study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Article
- pH-responsive ion release kinetics of a chitosan-based hydrogel incorporating nanohydroxyapatite and sodium fluoride for enamel remineralization.BMC oral health · 2026Article
- Review
- Size-controllable synthesis of hydroxyapatite nanorods via fluorine modulation: applications in dental adhesives for enhanced enamel remineralization.BMC oral health · 2025Article
- Ion release dynamics of bioactive resin cement under variable pH conditions.Frontiers in oral health · 2025Article
- Ion Release and Apatite Formation of Resin Based Pit and Fissure Sealants Containing 45S5 Bioactive Glass.Polymers · 2024Article
- Brief Narrative Review on Commercial Dental Sealants-Comparison with Respect to Their Composition and Potential Modifications.Materials (Basel, Switzerland) · 2023Review
- Effect of a bioactive pit and fissure sealant on demineralized human enamel: in vitro study.BMC oral health · 2022Article
- Penetration ability and microhardness of infiltrant resin and two pit and fissure sealants in primary teeth with early enamel lesions.Scientific reports · 2022Article
- Long-term ion release, fluoride recharge, pH modulation, and mechanical aging of an experimental ACP-based composite compared with contemporary bioactive restorative materials.Journal of oral biology and craniofacial researchArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To assess- the release of calcium and phosphate ions from a fissure sealant containing amorphous calcium phosphate (ACP), and to determine the re-release capacity of these ions when charged with a solution containing casein phosphopeptide-amorphous calcium phosphate (CPP-ACP). Nine blocks of ACP resin-based sealant were prepared and immersed in three solutions at different pH (4.0, 5.5, 7.0), and calcium and phosphate ion release was measured with ion chromatography at 1, 3, 5, 7, 14, 21 and 28 days after immersion. Sixty days after immersion, each block was charged with CPP-ACP solution in three 7-day cycles to investigate the re-release of these ions, which was measured on days 1, 3, and 7. No difference was observed in initial calcium ion release at pH 4.0 and pH 5.5. At both values, ion release was significantly higher than at pH 7.0 (p<0.001). Initial phosphate release was significantly different among the three pH values (p<0.001). After re-charging the specimens, calcium ion re-release was greater than phosphate ion release. Initial ion release from ACP resin-based sealant was greatest at the lowest pH. Ion release decreased with time. As the number of recharge cycles increased, ion re-release also improved. Phosphate ion re-release required more recharge cycles than calcium ion re-release.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.