ArticlePloS one2020
A one-year hospital-based prospective COVID-19 open-cohort in the Eastern Mediterranean region: The Khorshid COVID Cohort (KCC) study.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 7 of them syntheses that pooled it.
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Who cites it
29 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Effects of SARS-CoV-2 infections in patients with cancer on mortality, ICU admission and incidence: a systematic review with meta-analysis involving 709,908 participants and 31,732 cancer patients.Journal of cancer research and clinical oncology · 2023Pooled it
- Pooled it
- Psychiatric and neuropsychiatric sequelae of COVID-19 - A systematic review.Brain, behavior, and immunity · 2021Pooled it
- Cardiovascular diseases burden in COVID-19: Systematic review and meta-analysis.The American journal of emergency medicine · 2021Pooled it
- The association of smoking status with SARS-CoV-2 infection, hospitalization and mortality from COVID-19: a living rapid evidence review with Bayesian meta-analyses (version 7).Addiction (Abingdon, England) · 2021Pooled it
- Effects of cancer on patients with COVID-19: a systematic review and meta-analysis of 63,019 participants.Cancer biology & medicine · 2021Pooled it
- Global prevalence of prolonged gastrointestinal symptoms in COVID-19 survivors and potential pathogenesis: A systematic review and meta-analysis.F1000Research · 2021Pooled it
- A mixture cure modeling framework for survival analysis of hospitalized COVID-19 patients: implications for hospital resource management.BMC medical informatics and decision making · 2026Article
- Factors and Outcomes Attributable to Weaning and Decannulation from Ventilation after Tracheostomy.JMA journal · 2025Article
- Sleep Disturbances as a Consequence of Long COVID-19: Insights from Actigraphy and Clinimetric Examinations-An Uncontrolled Prospective Observational Pilot Study.Journal of clinical medicine · 2024Article
- Post-discharge health assessment in survivors of coronavirus disease: a time-point analysis of a prospective cohort study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023Article
- Target Trial Emulation Using Hospital-Based Observational Data: Demonstration and Application in COVID-19.Life (Basel, Switzerland) · 2023Article
- Factors Associated with Self-Reported Post/Long-COVID-A Real-World Data Study.International journal of environmental research and public health · 2022Article
- Article
- Severity of Disease and COVID-19 Complications During Hospital Stay: A Prospective Cohort Study.Archives of Iranian medicine · 2022Article
- IoT-Based COVID-19 Diagnosing and Monitoring Systems: A Survey.IEEE access : practical innovations, open solutions · 2022Article
- Gastrointestinal manifestations in patients with coronavirus disease-2019 (COVID-19): Impact on clinical outcomes.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2022Article
- Clinical characteristics of COVID-19-infected cancer patients, Isfahan, Iran.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2022Article
- Risk Factors for In-Hospital Mortality among Patients with Coronavirus-19 in Isfahan City, Iran.Advanced biomedical research · 2022Article
- Article
Corrections and comments
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Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The COVID-19 is rapidly scattering worldwide, and the number of cases in the Eastern Mediterranean Region is rising. Thus, there is a need for immediate targeted actions. We designed a longitudinal study in a hot outbreak zone to analyze the serial findings between infected patients for detecting temporal changes from February 2020. In a hospital-based open-cohort study, patients are followed from admission until one year from their discharge (the 1st, 4th, 12th weeks, and the first year). The patient recruitment phase finished at the end of August 2020, and the follow-up continues by the end of August 2021. The measurements included demographic, socio-economics, symptoms, health service diagnosis and treatment, contact history, and psychological variables. The signs improvement, death, length of stay in hospital were considered primary, and impaired pulmonary function and psychotic disorders were considered main secondary outcomes. Moreover, clinical symptoms and respiratory functions are being determined in such follow-ups. Among the first 600 COVID-19 cases, 490 patients with complete information (39% female; the average age of 57±15 years) were analyzed. Seven percent of these patients died. The three main leading causes of admission were: fever (77%), dry cough (73%), and fatigue (69%). The most prevalent comorbidities between COVID-19 patients were hypertension (35%), diabetes (28%), and ischemic heart disease (14%). The percentage of primary composite endpoints (PCEP), defined as death, the use of mechanical ventilation, or admission to an intensive care unit was 18%. The Cox Proportional-Hazards Model for PCEP indicated the following significant risk factors: Oxygen saturation < 80% (HR = 6.3; [CI 95%: 2.5,15.5]), lymphopenia (HR = 3.5; [CI 95%: 2.2,5.5]), Oxygen saturation 80%-90% (HR = 2.5; [CI 95%: 1.1,5.8]), and thrombocytopenia (HR = 1.6; [CI 95%: 1.1,2.5]). This long-term prospective Cohort may support healthcare professionals in the management of resources following this pandemic.
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