Evidence map›Paper›PMID 33151773›Full record

ArticleJCO global oncology2020

Body Mass Index, Chemotherapy-Related Weight Changes, and Disease-Free Survival in Haitian Women With Nonmetastatic Breast Cancer.

Temidayo Fadelu, Ruth Damuse, Joarly Lormil, Elizabeth Pecan, Lauren Greenberg, Cyrille Dubuisson, Viergela Pierre, Scott A Triedman, Lawrence N Shulman, Timothy R Rebbeck

Open access · goldAbstract read
In one paragraph

Article in JCO global oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 9 citations in OpenAlex.

  1. The effect of BMI on survival outcome of breast cancer patients: a systematic review and meta-analysis.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Pooled it
  2. Pooled it
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Temidayo FadeluDana-Farber Cancer Institute, Boston, MA.ORCID 0000-0002-1323-4119
Ruth DamuseHôpital Universitaire de Mirebalais, Mirebalais, Haiti.
Joarly LormilHôpital Universitaire de Mirebalais, Mirebalais, Haiti.
Elizabeth PecanWharton Business School, University of Pennsylvania, Philadelphia, PA.
Lauren GreenbergPartners In Health, Boston, MA.ORCID 0000-0003-1675-3683
Cyrille DubuissonHôpital Universitaire de Mirebalais, Mirebalais, Haiti.
Viergela PierreHôpital Universitaire de Mirebalais, Mirebalais, Haiti.
Scott A TriedmanDana-Farber Cancer Institute, Boston, MA.ORCID 0000-0002-0894-2196
Lawrence N ShulmanAbramson Cancer Center, University of Pennsylvania, Philadelphia, PA.ORCID 0000-0001-8661-473X
Timothy R RebbeckDana-Farber Cancer Institute, Boston, MA.ORCID 0000-0002-4799-1900
University of Pennsylvania · USBrown University · USDana-Farber Cancer Institute · USHarvard University · USPartners In Health · US

Funding

Transdisciplinary Research in Energetics and Cancer (TREC) Training GrantR25CA203650 · NCI · YALE UNIVERSITY · PI IRWIN, MELINDA L · 2016 to 2025
$2.9M
NCI NIH HHS R25 CA203650
6 · The paper itself

Abstract

purposeFew studies have explored the relationship between body habitus and breast cancer outcomes in Caribbean women of African ancestry. This study evaluates the association between body mass index (BMI) and disease-free survival (DFS) in a retrospective cohort of 224 female Haitian patients with nonmetastatic breast cancer. PATIENTS AND

methodsBMI was obtained from the medical records and categorized as normal weight (< 25 kg/m

resultsEighty-three patients (37.1%) were normal weight, 66 (29.5%) were overweight, and 75 (33.5%) were obese. There were no statistical differences in baseline characteristics or treatments received by BMI group. Twenty-six patients died and 73 had disease recurrence. Median DFS was 41.1 months. Kaplan-Meier estimates showed no significant DFS differences by BMI categories. After controlling for confounders, normal weight patients, when compared with overweight and obese patients, had adjusted hazard ratios of 0.85 (95% CI, 0.49 to 1.49) and 0.90 (95% CI, 0.52 to 1.55), respectively. Overall, mean weight loss of 2% of body weight was noted over the course of adjuvant chemotherapy. Patients who were postmenopausal (

conclusionBaseline BMI and weight changes during adjuvant chemotherapy did not have an impact on DFS in this cohort. Future prospective studies in similar Caribbean breast cancer cohorts are needed to verify study findings.

Indexed as

Breast NeoplasmsBody Mass IndexCaribbean RegionDisease-Free SurvivalFemaleHaitiHumansNeoplasm Recurrence, LocalProspective StudiesRetrospective Studies

Identifiers

PMID33151773
PMCPMC7713562
OpenAlexW3096417907

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.