Evidence map›Paper›PMID 33151614›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2021

Racial disparities in preemptive waitlisting and deceased donor kidney transplantation: Ethics and solutions.

Peter P Reese, Sumit Mohan, Kristen L King, Winfred W Williams, Vishnu S Potluri, Meera N Harhay, Nwamaka D Eneanya

Abstract read
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In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Restoring time lost to race-based medicine.Nature reviews. Urology · 2026
    Article
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  15. Care of Adults with Advanced Chronic Kidney Disease.Journal of clinical medicine · 2024
    Review
  16. Association Between Transplant Center Continuity and Access to a Second Kidney Transplant in Patients With Allograft Failure.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2024
    Article
  17. Article
  18. Utility of the Kidney Failure Risk Equation and Estimated GFR for Estimating Time to Kidney Failure in Advanced CKD.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2023
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Peter P ReeseDepartment of Medicine, Renal-Electrolyte and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.ORCID 0000-0003-1440-069X
Sumit MohanDepartment of Medicine, Division of Nephrology, Columbia University College of Physicians & Surgeons and New York Presbyterian Hospital, New York, New York.ORCID 0000-0002-5305-9685
Kristen L KingDepartment of Medicine, Division of Nephrology, Columbia University College of Physicians & Surgeons and New York Presbyterian Hospital, New York, New York.
Winfred W WilliamsDivision of Nephrology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
Vishnu S PotluriDepartment of Medicine, Renal-Electrolyte and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Meera N HarhayDepartment of Medicine, Drexel University College of Medicine, Philadelphia, Pennsylvania.ORCID 0000-0001-6500-2814
Nwamaka D EneanyaDepartment of Medicine, Renal-Electrolyte and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

Funding

Increasing Minority Population Awareness through Community Teaching for Improved Organ Donation (IMPACT for Improved Organ Donation)R01DK114893 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MOHAN, SUMIT · 2017 to 2021
$1.2M
Patterns and Implications of Functional Decline Among Kidney Transplant CandidatesK23DK105207 · NIDDK · DREXEL UNIVERSITY · PI HARHAY, MEERA NAIR · 2015 to 2019
$861k
Mentored research in solid organ transplantation: outcomes using organs from Hepatitis C virus infected donors for uninfected recipientsK24AI146137 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI REESE, PETER PHILIP · 2019 to 2023
$671k
NIH HHS K23DK105207NIH HHS K24AI146137NIH HHS R01DK114893NIH HHS R01MD14161NIH HHS U01DK114893
6 · The paper itself

Abstract

Kidney transplantation prior to dialysis, known as "preemptive transplant," enables patients to live longer and avoid the substantial quality of life burdens due to chronic dialysis. Deceased donor kidneys are a public resource that ought to provide health benefits equitably. Unfortunately, White, better educated, and privately insured patients enjoy disproportionate access to preemptive transplantation using deceased donor kidneys. This problem has persisted for decades and is exacerbated by the first-come, first-served approach to kidney allocation for predialysis patients. In this Personal Viewpoint, we describe the diverse barriers to preemptive waitlisting and kidney transplant. The analysis focuses on healthcare system features that particularly disadvantage Black patients, such as the waitlisting eligibility criterion of a single glomerular filtration rate or creatinine clearance ≤20 ml/min, and neglect of wide variation in the rate of progression to end-stage kidney disease (ESKD) in allocating preemptive transplants. We propose initiatives to improve equity including: (1) standardization of waitlisting eligibility criteria related to kidney function; (2) aggressive education for clinicians about early transplant referral; (3) innovations in electronic medical record capabilities; and (4) rapid status 7 listing by centers. If those initiatives fail, the transplant field should consider eliminating preemptive waitlisting and transplantation with deceased donor kidneys.

Indexed as

Kidney Failure, ChronicKidney TransplantationHumansKidneyQuality of LifeWaiting Listsclinical research / practicedialysisdisparitiesethics and public policyethnicity / racekidney transplantation / nephrologyorgan allocationorgan procurement and allocationwaitlist management

Identifiers

PMID33151614

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.