ReviewFASEB journal : official publication of the Federation of American Societies for Experimental Biology2021
Integrative cardiovascular control in women: Regulation of blood pressure, body temperature, and cerebrovascular responsiveness.
Review in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.
- A systematic review, meta-analysisJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024Pooled it
- Sex differences in the sympathetic neurocirculatory responses to chemoreflex activation.The Journal of physiology · 2022Trial
- Role of autonomic receptors in ethyl ferulate-induced cardiovascular effects in normotensive and hypertensive female rats.Pflugers Archiv : European journal of physiology · 2026Article
- Female sex as a possible factor associated with favorable long-term outcomes in off-pump coronary artery bypass surgery.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2026Article
- A 3D-1D-0D multiscale model of the neuro-glial-vascular unit for synaptic and vascular dynamics in the dorsal vagal complex.Journal of mathematical biology · 2025Article
- Microcirculation-Promoting Effect of Escin on Cutaneous Tissue via Gsk3β Down-Regulation.Current issues in molecular biology · 2025Article
- Is the FIFA 11+ Warm-Up Effective for Inducing Acute Knee Adaptations in Recreational Soccer Players?Journal of functional morphology and kinesiology · 2025Article
- Article
- Gut microbiota has the potential to improve health of menopausal women by regulating estrogen.Frontiers in endocrinology · 2025Review
- A possible important regulatory role of estrogen in obstructive sleep apnea hypoventilation syndrome.Frontiers in medicine · 2025Review
- A gender-integrated biopsychosocial model to understand cardiovascular risk in women working under environmental hazards: the case of chronic intermittent hypoxia.Frontiers in public health · 2025Review
- Temperature and carotid intima-medial thickness: The coronary artery risk development in young adults (CARDIA) study.The Science of the total environment · 2024Article
- The role of peripheral venous distension reflex in regulating hemodynamics: mini review.Autonomic neuroscience : basic & clinical · 2024Review
- The effect of the menstrual cycle phases on back squat performance, jumping ability and psychological state in women according to their level of performance -a randomized three-arm crossover study.BMC sports science, medicine & rehabilitation · 2024Article
- Inflammaging and Brain Aging.International journal of molecular sciences · 2024Review
- Exploring the Feasibility of Estrogen Replacement Therapy as a Treatment for Perimenopausal Depression: A Comprehensive Literature Review.Medicina (Kaunas, Lithuania) · 2024Review
- Circadian Rhythms of Body Temperature and Locomotor Activity in Spontaneously Hypertensive Rats under Frequent Changes in Light Conditions.Pathophysiology : the official journal of the International Society for Pathophysiology · 2024Article
- Attenuated pulsatile transition to the cerebral vasculature during high-intensity interval exercise in young healthy men.Experimental physiology · 2023Article
- Combining hypoxia with thermal stimuli in humans: physiological responses and potential sex differences.American journal of physiology. Regulatory, integrative and comparative physiology · 2023Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Over the past several decades, it has become increasingly clear that women have distinct cardiovascular profiles compared to men. In this review, our goal is to provide an overview of the literature regarding the influences of female sex and reproductive hormones (primarily estradiol) on mechanisms of cardiovascular control relevant to regulation of blood pressure, body temperature, and cerebral blood flow. Young women tend to have lower resting blood pressure compared with men. This sex difference is reversed at menopause, when women develop higher sympathetic nerve activity and the risk of systemic hypertension increases sharply as postmenopausal women age. Vascular responses to thermal stress, including cutaneous vasodilation and vasoconstriction, are also affected by reproductive hormones in women, where estradiol appears to promote vasodilation and heat dissipation. The influence of reproductive hormones on cerebral blood flow and sex differences in the ability of the cerebral vasculature to increase its blood flow (cerebrovascular reactivity) are relatively new areas of investigation. Sex and hormonal influences on integrative blood flow regulation have further implications during challenges to physiological homeostasis, including exercise. We propose that increasing awareness of these sex-specific mechanisms is important for optimizing health care and promotion of wellness in women across the life span.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.