Evidence map›Paper›PMID 33151421›Full record

ArticleSurgical case reports2020

A case of aggressive aortic prosthetic valve endocarditis aggressive caused by Staphylococcus lugdunensis.

Kazuhiro Yamazaki, Kenji Minakata, Kazuhisa Sakamoto, Jiro Sakai, Yujiro Ide, Masahide Kawatou, Hideo Kanemitsu, Tadashi Ikeda, Kenji Minatoya, Ryuzo Sakata

Open access · goldAbstract read
In one paragraph

Article in Surgical case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Indolenine-substituted pyrazole derivative 4e inhibits planktonicAntimicrobial agents and chemotherapy · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Kazuhiro YamazakiDepartment of Cardiovascular Surgery, Graduate of School of Medicine, Kyoto University, 54 Shogoin-Kawahara-Machi, Sakyo, Kyoto, Japan. yamakazu@kuhp.kyoto-u.ac.jp.ORCID http://orcid.org/0000-0002-5569-0446
Kenji MinakataDepartment of Cardiovascular Surgery, Graduate of School of Medicine, Kyoto University, 54 Shogoin-Kawahara-Machi, Sakyo, Kyoto, Japan.
Kazuhisa SakamotoDepartment of Cardiovascular Surgery, Graduate of School of Medicine, Kyoto University, 54 Shogoin-Kawahara-Machi, Sakyo, Kyoto, Japan.
Jiro SakaiDepartment of Cardiovascular Surgery, Graduate of School of Medicine, Kyoto University, 54 Shogoin-Kawahara-Machi, Sakyo, Kyoto, Japan.
Yujiro IdeDepartment of Cardiovascular Surgery, Graduate of School of Medicine, Kyoto University, 54 Shogoin-Kawahara-Machi, Sakyo, Kyoto, Japan.
Masahide KawatouDepartment of Cardiovascular Surgery, Graduate of School of Medicine, Kyoto University, 54 Shogoin-Kawahara-Machi, Sakyo, Kyoto, Japan.
Hideo KanemitsuDepartment of Cardiovascular Surgery, Graduate of School of Medicine, Kyoto University, 54 Shogoin-Kawahara-Machi, Sakyo, Kyoto, Japan.
Tadashi IkedaDepartment of Cardiovascular Surgery, Graduate of School of Medicine, Kyoto University, 54 Shogoin-Kawahara-Machi, Sakyo, Kyoto, Japan.
Kenji MinatoyaDepartment of Cardiovascular Surgery, Graduate of School of Medicine, Kyoto University, 54 Shogoin-Kawahara-Machi, Sakyo, Kyoto, Japan.
Ryuzo SakataDepartment of Cardiovascular Surgery, Graduate of School of Medicine, Kyoto University, 54 Shogoin-Kawahara-Machi, Sakyo, Kyoto, Japan.
Kyoto University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStaphylococcus lugdunensis is a coagulase-negative Staphylococcus species, which are weak pathogenic bacteria generally. However, the acute and severe pathogenicity of Staphylococcus lugdunensis infective endocarditis may be due to the rapid growth of large vegetation and consequent valve destruction. CASE PRESENTATION: The patient was an 81-year-old male who visited our hospital with chief complaints of low back pain and high fever. Four years before this visit, he had undergone aortic valve replacement for aortic regurgitation. He was found to be hypotensive. Although there is no heart murmur on auscultation and echocardiography revealed negative findings with aortic valve, a blood test showed increases in the white blood cell count and C-reactive protein concentration. On the next day, Gram-positive cocci were detected in a blood culture and echocardiography detected a large vegetation on the prosthetic valve with increased flow velocity. Therefore, he underwent redo aortic valve replacement emergently. Staphylococcus lugdunensis was identified in blood samples and vegetation culture. Consequently, the patient was treated with antibiotics for 5 weeks after the operation and discharged home.

conclusionsWe experienced rapidly progressive prosthetic valve endocarditis caused by Staphylococcus lugdunensis. Hence, Staphylococcus lugdunensis infective endocarditis requires aggressive treatment, and the pathogenicity of this coagulase-negative Staphylococcus with high drug susceptibility should not be underestimated.

Indexed as

Aortic valve replacementProsthetic valve endocarditisStaphylococcus lugdunensis

Identifiers

PMID33151421
PMCPMC7644629
OpenAlexW3095221254

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.