Evidence map›Paper›PMID 33151124›Full record

ArticleRNA biology2021

Gastrodin promotes CNS myelination via a lncRNA Gm7237/miR-142a/MRF pathway.

Yue Shu, Tianyuan Luo, Mingda Wang, Yu Zhang, Lin Zhang, Zhi Xiao, Qianxing Wang, Qiang Zhang, Jia Zou, Changyin Yu and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in RNA biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Gastrodin: a comprehensive pharmacological review.Naunyn-Schmiedeberg's archives of pharmacology · 2024
    Review
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Yue ShuKey Laboratory of Brain Science, Zunyi Medical University, Zunyi, China.
Tianyuan LuoGuizhou Key Laboratory of Anesthesia and Organ Protection, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Mingda WangKey Laboratory of Brain Science, Zunyi Medical University, Zunyi, China.
Yu ZhangGuizhou Key Laboratory of Anesthesia and Organ Protection, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Lin ZhangGuizhou Key Laboratory of Anesthesia and Organ Protection, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Zhi XiaoKey Laboratory of Brain Science, Zunyi Medical University, Zunyi, China.
Qianxing WangDepartment of Cell Biology, Zunyi Medical University, Zunyi, China.
Qiang ZhangKey Laboratory of Brain Science, Zunyi Medical University, Zunyi, China.
Jia ZouKey Laboratory of Brain Science, Zunyi Medical University, Zunyi, China.
Changyin YuKey Laboratory of Brain Science, Zunyi Medical University, Zunyi, China.
Shangfu XuKey Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, China.
Tian YuKey Laboratory of Brain Science, Zunyi Medical University, Zunyi, China.
Liang ZhouKey Laboratory of Brain Science, Zunyi Medical University, Zunyi, China.
Shouyang YuKey Laboratory of Brain Science, Zunyi Medical University, Zunyi, China.ORCID 0000-0003-3198-4025
Zunyi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Treatment of central nervous system (CNS) demyelination is greatly hindered by lack of the knowledge regarding to underlying molecular mechanisms as well as therapeutic agents. Here, we report a novel small molecule agent, gastrodin (GAS), which can significantly promote CNS myelination in

Indexed as

AnimalsBenzyl AlcoholsCentral Nervous SystemGene Expression RegulationGlucosidesMiceMice, Inbred C57BLMicroRNAsMyelin SheathRNA, Long NoncodingTranscription FactorsBenzyl AlcoholsgastrodinGlucosidesMicroRNAsMirn142 microRNA, mousemyelin gene regulatory factor, mouseRNA, Long NoncodingTranscription FactorsGastrodinlncRNAmicroRNAmyelination

Identifiers

PMID33151124
PMCPMC8354603
OpenAlexW3095121414

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.