Evidence map›Paper›PMID 33150778›Full record

ArticleChronic obstructive pulmonary diseases (Miami, Fla.)2021

Treatment Preferences of Patients with Chronic Obstructive Pulmonary Disease: Results from Qualitative Interviews and Focus Groups in the United Kingdom, United States, and Germany.

Melanie Schroeder, Katie Hall, Lina Eliasson, Sophia Bracey, Necdet B Gunsoy, Jake Macey, Paul W Jones, Afisi S Ismaila

Open access · diamondAbstract read
In one paragraph

Article in Chronic obstructive pulmonary diseases (Miami, Fla.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 4 countries.

Melanie SchroederValue Evidence and Outcomes, GlaxoSmithKline plc., Brentford, United Kingdom.
Katie HallPatient Centred Outcomes, ICON plc., London, United Kingdom.
Lina EliassonPatient Centred Outcomes, ICON plc., London, United Kingdom.
Sophia BraceyPatient Centred Outcomes, ICON plc., Abingdon, United Kingdom.
Necdet B GunsoyValue Evidence and Outcomes, GlaxoSmithKline plc., Uxbridge, United Kingdom.
Jake MaceyPatient Centred Outcomes, ICON plc., Abingdon, United Kingdom.
Paul W JonesGlobal Respiratory Therapy Area, GlaxoSmithKline plc., Brentford, United Kingdom.
Afisi S IsmailaValue Evidence and Outcomes, GlaxoSmithKline plc., Collegeville, Pennsylvania, United States.
GlaxoSmithKline (United States) · USSouth College · USGlaxoSmithKline (United Kingdom) · GBImpact · CA

Funding

GlaxoSmithKline plc. CTT206455/NCT03046069
6 · The paper itself

Abstract

backgroundA wide range of therapeutic regimens, including single-inhaler triple therapies (SITTs), are now available for the maintenance treatment of chronic obstructive pulmonary disease (COPD). Thus, an improved understanding of patient preferences may be valuable to inform physician prescribing decisions. This study was performed to assess the factors considered by patients when making decisions about their COPD treatments using qualitative techniques.

methodsIn the United Kingdom, United States and Germany, individual qualitative interviews (n=10 per country) and focus groups (1 per country; [United Kingdom, n=4; United States, n=6; Germany, n=6 participants]) were conducted. Interviews and focus groups were semi‑structured, lasting approximately 60 minutes, and focused on treatment preferences. Data were analyzed according to emerging themes identified from the interviews; qualitative thematic analysis of the data was performed using specialist software.

resultsIn interviews and focus groups, efficacy, ease of use, and lower frequency of use were favored attributes for current treatment, while side effects, medication taste, and more complex administration techniques were key dislikes. In interviews, most participants would consider a switch in medication, mainly for improved efficacy, but also to reduce medication frequency or following physician advice. Overall, efficacy and ease of use were the 2 most important attributes reported in interviews in all 3 countries.

conclusionPatients with COPD have preferences for certain attributes of medication, highlighting the multi-faceted nature of treatment effectiveness and the importance of the delivery device.These results were subsequently used to inform the design of a discrete choice experiment.

Indexed as

chronic obstructive pulmonary disease (COPD)discrete choice experiment (DCE)focus groupinterviewmulti-countryqualitative researchtreatment preferences

Identifiers

PMID33150778
PMCPMC8047617
OpenAlexW3097526783

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.