Evidence map›Paper›PMID 33150640›Full record

Trial reportThe International journal of eating disorders2020

Mediators of change in cognitive behavior therapy and interpersonal psychotherapy for eating disorders: A secondary analysis of a transdiagnostic randomized controlled trial.

Katy Sivyer, Elizabeth Allen, Zafra Cooper, Suzanne Bailey-Straebler, Marianne E O'Connor, Christopher G Fairburn, Rebecca Murphy

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The International journal of eating disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

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  11. The growing field of digital psychiatry: current evidence and the future of apps, social media, chatbots, and virtual reality.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Katy SivyerDepartment of Psychiatry, Oxford University, Oxford, UK.ORCID 0000-0003-4349-0102
Elizabeth AllenDepartment of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UK.
Zafra CooperDepartment of Psychiatry, Oxford University, Oxford, UK.ORCID 0000-0001-7963-656X
Suzanne Bailey-StraeblerDepartment of Psychiatry, Oxford University, Oxford, UK.
Marianne E O'ConnorDepartment of Psychiatry, Oxford University, Oxford, UK.
Christopher G FairburnDepartment of Psychiatry, Oxford University, Oxford, UK.
Rebecca MurphyDepartment of Psychiatry, Oxford University, Oxford, UK.
University of Oxford · GBLondon School of Hygiene & Tropical Medicine · GB

Funding

Wellcome Trust 046386
6 · The paper itself

Abstract

objectiveUnderstanding the mechanisms of action of psychological treatments is a key first step in refining and developing more effective treatments. The present study examined hypothesized mediators of change of enhanced cognitive behavior therapy (CBT-E) and interpersonal psychotherapy for eating disorders (IPT-ED).

methodA series of mediation studies were embedded in a randomized controlled trial (RCT) comparing 20 weeks of CBT-E and IPT-ED in a transdiagnostic, non-underweight sample of patients with eating disorders (N = 130) consecutively referred to the service. Three hypothesized mediators of change in CBT-E (regular eating, weighing frequency, and shape checking) and the key hypothesized mediator of IPT-ED (interpersonal problem severity) were studied.

resultsThe data supported regular eating as being a mediator of the effect of CBT-E on binge-eating frequency. The findings were inconclusive regarding the role of the other putative mediators of the effects of CBT-E; and were similarly inconclusive for interpersonal problem severity as a mediator of the effect of IPT-ED. DISCUSSION: This research highlights the potential benefits of embedding mediation studies within RCTs to better understand how treatments work. The findings supported the role of regular eating in reducing patients' binge-eating frequency. Other key hypothesized mediators of CBT-E and IPT-ED were not supported, although the data were not inconsistent with them. Key methodological issues to address in future work include the need to capture both behavioral and cognitive processes of change in CBT-E, and identifying key time points for change in IPT-ED.

Indexed as

AdultCognitive Behavioral TherapyFeeding and Eating DisordersHumansInterpersonal PsychotherapyTreatment Outcomecognitive behavior therapyeating disorderinterpersonal psychotherapymediatortransdiagnostictreatment personalization

Identifiers

PMID33150640
PMCPMC7756462
OpenAlexW3094481030

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.